Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: ileum ✕ Assay: analysis ✕ Clear

Tachykinin signaling defines distinct populations of glia in the enteric nervous system.

PMID 41512855 · PMC12832054 · Neuron · 2026 · 8 claims · 8 setups

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Mucosal and muscularis glia are transcriptionally distinct populations, with mucosal glia resembling microglia and muscularis glia resembling satellite glia/astrocytes

ileum gfp+ intestinal intestine bulk scrna-seq bayesprism
Deciphering immune and cellular reprogramming during the progression from inflammatory bowel disease to colorectal cancer using multi-omics single-cell and spatial transcriptomics.

PMID 42001187 · PMC13122952 · Journal of translational medicine · 2026 · 8 claims · 5 setups

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CEACAM5 is consistently upregulated across Crohn's disease and ulcerative colitis samples and links epithelial activation in IBD to tumorigenic processes in CRC

intestinal colorectal single-cell serum bulk single-cell spatial
Genetic evidence supporting obesity as a risk factor for lung squamous cell carcinoma and the identification of MFAP1 as a shared genetic target.

PMID 41820721 · PMC13096280 · Discover oncology · 2026 · 8 claims · 8 setups

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BMI and LUSC show a significant positive genome-wide genetic correlation, robust to constrained-intercept sensitivity analysis and replicated by GNOVA.

gwas gtex scrna-seq ldsc gnova ρ-hess
A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients.

PMID 36694043 · PMC9873918 · Communications biology · 2023 · 8 claims · 8 setups

Has reproduction · 83

Disease-specific temporal (dynamic) gene expression and splicing signatures, distinct from fixed timepoint differential expression, can be derived from DSS and adoptive transfer colitis models to capture acute-chronic disease dynamics

colon blood distal ibd bulk qpcr histopathology
Paneth cell SIRT1 deficiency increases intestinal stress resistance by modulating the gut microbiota.

PMID 41826553 · PMC13076647 · EMBO reports · 2026 · 8 claims · 8 setups

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Generated a novel Paneth-cell-specific SIRT1 knockout mouse model (SIRT1 PKO, Sirt1 f/f;Defa6-Cre+)

small immune facs-sorted ileum single-cell facs qpcr
Dietary conjugated linoleic acid enhances resistance to Salmonella infection by promoting PPARγ-mediated metabolic reprogramming and effector function in CD8⁺ T cells.

PMID 41964110 · PMC13078244 · Gut microbes · 2026 · 8 claims · 12 setups

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Dietary CLA supplementation enhances host resistance to Salmonella Typhimurium infection

ileal mice serum culture 16s untargeted bulk

Experiments

Tachykinin signaling defines distinct populations of glia in the enteric nervous system.

Deciphering immune and cellular reprogramming during the progression from inflammatory bowel disease to colorectal cancer using multi-omics single-cell and spatial transcriptomics.

Genetic evidence supporting obesity as a risk factor for lung squamous cell carcinoma and the identification of MFAP1 as a shared genetic target.

A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients.

Paneth cell SIRT1 deficiency increases intestinal stress resistance by modulating the gut microbiota.

Dietary conjugated linoleic acid enhances resistance to Salmonella infection by promoting PPARγ-mediated metabolic reprogramming and effector function in CD8⁺ T cells.