Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements.
PMID 18174224 · PMC2238826 · Nucleic acids research · 2008 · 6 claims · 5 setups
Standard genome annotation pipelines misannotate selenoprotein genes because they rely on UGA as a universal stop codon, failing to recognize its dual role as the selenocysteine-recoding codon.
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Has reproduction · 46
De novo transcriptome assembly and comprehensive assessment provide insight into fruiting body formation of Sparassis latifolia.
PMID 35773379 · PMC9247108 · Scientific reports · 2022 · 6 claims · 7 setups
De novo transcriptome assembly of S. latifolia produced 48,549 unigenes, 71.53% (34,728) of which were annotated against KEGG, GO, and/or KOG databases
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Has reproduction · 61
Comprehensive transcriptome study to develop molecular resources of the copepod Calanus sinicus for their potential ecological applications.
PMID 24982883 · PMC4055022 · BioMed research international · 2014 · 8 claims · 8 setups
Illumina RNA-Seq with Trinity de novo assembly produced a C. sinicus transcriptome of 69,751 contigs (average 928.8 bp, N50 1,127 bp) from 58.9 million reads.
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Genome sequences and great expectations.
PMID 11178275 · PMC150431 · Genome biology · 2001 · 8 claims · 3 setups
Function is known or can be predicted for an average of 62% of proteins across 31 analyzed genomes.
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Comparative mapping of expressed sequence tags containing microsatellites in rainbow trout (Oncorhynchus mykiss).
PMID 15836796 · PMC1090573 · BMC genomics · 2005 · 8 claims · 7 setups
89 polymorphic microsatellite markers were developed from rainbow trout EST-derived cDNA clones
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Has reproduction · 73
Transcriptome assembly, profiling and differential gene expression analysis of the halophyte Suaeda fruticosa provides insights into salt tolerance.
PMID 25943316 · PMC4422317 · BMC genomics · 2015 · 7 claims · 6 setups
De novo assembly of the S. fruticosa transcriptome (Velvet/Oases k-45, CDHIT-EST) produced 54,526 high-quality unigenes with N50 of 957 bp
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Babelomics: advanced functional profiling of transcriptomics, proteomics and genomics experiments.
PMID 18515841 · PMC2447758 · Nucleic acids research · 2008 · 8 claims · 5 setups
Babelomics is a web suite offering both conventional functional enrichment methods and more advanced gene set analysis (GSA) methods, a combination offered by only one other tool (FuncAssociate) among competitors.
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Has reproduction · 83
Macrel: antimicrobial peptide screening in genomes and metagenomes.
PMID 33384902 · PMC7751412 · PeerJ · 2020 · 8 claims · 8 setups
Macrel is an end-to-end pipeline that predicts high-quality AMP candidates from peptides, contigs, or reads of (meta)genomes
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Has reproduction · 91
Chromosome-level genome assembly of agar-producing red seaweed Gracilaria vermiculophylla.
PMID 41629338 · PMC12966425 · Scientific data · 2026 · 8 claims · 8 setups
Assembled the first chromosome-level genome of G. vermiculophylla: 77.5 Mb, 22 pseudochromosomes, contig N50 2.61 Mb, scaffold N50 3.16 Mb
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Genome reannotation of Escherichia coli CFT073 with new insights into virulence.
PMID 19930606 · PMC2785843 · BMC genomics · 2009 · 8 claims · 7 setups
Reannotation excluded 608 CDSs from the original RefSeq annotation, mostly unfunctional 'hypothetical'/'putative' genes
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Has reproduction · 100
Conservation and losses of non-coding RNAs in avian genomes.
PMID 25822729 · PMC4378963 · PloS one · 2015 · 8 claims · 6 setups
Homology-based covariance model (Rfam CM) annotation, combined with tRNAscan-SE and miRBase-derived models, identifies ncRNA loci across 48 avian genomes
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Has reproduction · 100
FA-nf: A Functional Annotation Pipeline for Proteins from Non-Model Organisms Implemented in Nextflow.
PMID 34681040 · PMC8535801 · Genes · 2021 · 8 claims · 4 setups
FA-nf, implemented in Nextflow with Docker/Singularity containerization, integrates NCBI BLAST+, DIAMOND, InterProScan, and KEGG (KAAS/KofamKOALA) into a single functional annotation pipeline.
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DBD--taxonomically broad transcription factor predictions: new content and functionality.
PMID 18073188 · PMC2238844 · Nucleic acids research · 2008 · 8 claims · 3 setups
DBD is a database of predicted sequence-specific DNA-binding transcription factors covering over 700 publicly available proteomes, up from 150 in the initial version.
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The human L-threonine 3-dehydrogenase gene is an expressed pseudogene.
PMID 12361482 · PMC131051 · BMC genetics · 2002 · 8 claims · 7 setups
The human TDH gene is located at chromosome 8p23-22, spans 10 kb, and has 8 exons that would be expected to encode a 369-residue ORF.
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PeroxisomeDB: a database for the peroxisomal proteome, functional genomics and disease.
PMID 17135190 · PMC1747181 · Nucleic acids research · 2007 · 8 claims · 6 setups
PeroxisomeDB integrates the complete peroxisomal proteome of Homo sapiens and Saccharomyces cerevisiae into interrelated 'Genes', 'Functions', 'Metabolic pathways' and 'Diseases' sections with links to NCBI, ENSEMBL and UCSC
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Has reproduction · 84
Pharokka: a fast scalable bacteriophage annotation tool.
PMID 36453861 · PMC9805569 · Bioinformatics (Oxford, England) · 2023 · 8 claims · 5 setups
Pharokka is a one-line, fast, scalable bacteriophage annotation tool producing standards-compliant outputs, installable via a two-line bioconda command
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Molecular archeology of L1 insertions in the human genome.
PMID 12372140 · PMC134481 · Genome biology · 2002 · 8 claims · 4 setups
TSDfinder, a new algorithm, refines RepeatMasker-identified L1 boundaries by locating poly(A) tails, TSDs, and inversion breakpoints
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Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina.
PMID 14519200 · PMC328454 · Genome biology · 2003 · 8 claims · 5 setups
Annotation of 8,633 high-quality non-mitochondrial/non-ribosomal ESTs shows 57% represent known genes and 43% are unknown or novel, with M15E having the highest proportion of novel ESTs
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Retropseudogenes derived from the human Ro/SS-A autoantigen-associated hY RNAs.
PMID 15817567 · PMC1074747 · Nucleic acids research · 2005 · 8 claims · 8 setups
966 pseudogenes derived from the four human Y (hY) RNAs were characterized in the human genome
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MODBASE, a database of annotated comparative protein structure models and associated resources.
PMID 18948282 · PMC2686492 · Nucleic acids research · 2009 · 8 claims · 8 setups
MODBASE contains 5,152,695 reliable comparative protein structure models for 1,593,209 unique protein sequences.