Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
-
Full-text index only
From Pasteur to genomics: progress and challenges in infectious diseases.
PMID 15516917 · PMC7096024 · Nature medicine · 2004 · 8 claims · 8 setups
Genomic sequencing has revealed the blueprint of most pathogens, enabling new diagnostics, therapeutics and vaccines including for previously uncultivable agents.
-
Full-text index only
SePaCS--a web-based application for classification of seroreactivity profiles.
PMID 17478503 · PMC1933220 · Nucleic acids research · 2007 · 8 claims · 4 setups
SePaCS is a freely available web-based tool that trains and applies multiple classification methods (4 Naive Bayes variants, SVM with RBF kernel, LDA, DLDA) to seroreactivity profiles and outputs results as a summary table plus a detailed PDF report
-
Full-text index only
The evolutionary dynamics of a rapidly mutating virus within and between hosts: the case of hepatitis C virus.
PMID 19911046 · PMC2768904 · PLoS computational biology · 2009 · 8 claims · 3 setups
The replication rate of the strain that initiates an infection has a strong effect on the fitness of the infection at the between-host level, even though the virus evolves rapidly within the host.
-
Full-text index only
Biocomputing enters its adolescence.
PMID 15960815 · PMC1175967 · Genome biology · 2005 · 8 claims · 8 setups
A 'match augmentation' algorithm efficiently matches structural motifs by prioritizing functionally significant residues, enabling function prediction between evolutionarily unrelated proteins
-
Full-text index only
Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study.
PMID 18205922 · PMC2374452 · Arthritis research & therapy · 2008 · 7 claims · 4 setups
A standardized 3D in vitro alginate bead model of chondrocytes stimulated with synovial fibroblast supernatants can be used to profile RA-related cartilage destruction genes
-
Full-text index only
Innate immune modulation by RNA viruses: emerging insights from functional genomics.
PMID 18654572 · PMC7097543 · Nature reviews. Immunology · 2008 · 8 claims · 7 setups
Influenza virus signals primarily through RIG-I to induce ISG expression, while West Nile virus signals through both RIG-I and MDA5 cooperatively.
-
Full-text index only
Flanking p10 contribution and sequence bias in matrix based epitope prediction: revisiting the assumption of independent binding pockets.
PMID 18925947 · PMC2600787 · BMC structural biology · 2008 · 8 claims · 3 setups
The extended matrix PP10 (built from a proline-containing peptide library) shows significant improvement in binding prediction over the original nine-residue matrix P9
-
Full-text index only
Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways.
PMID 19712456 · PMC2754444 · Journal of translational medicine · 2009 · 7 claims · 5 setups
31 HIV-modulated cellular proteins were identified as functionally associated with signaling events involved in angiogenesis
-
Full-text index only
ABO exon and intron analysis in individuals with the AweakB phenotype reveals a novel O1v-A2 hybrid allele that causes four missense mutations in the A transferase.
PMID 14617382 · PMC305365 · BMC genetics · 2003 · 8 claims · 7 setups
A novel O1v-A2 hybrid allele, containing four missense mutations, causes the A weak B phenotype in five individuals of African descent