Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• T cell-intrinsic VISTA expression promotes resistance to CTLA-4 blockade by restricting CD8+ T cell responses.

  PMID 41837284 · PMC12987620 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups

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  Loss of T cell-intrinsic VISTA enhances early priming and short-term expansion of CD8+ T cells but this initial advantage fails to confer durable tumor control

  tumor vsir cell-specific myeloid-specific flow adoptive peptide

• TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network.

  PMID 42020373 · PMC13102947 · Nature communications · 2026 · 8 claims · 8 setups

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  TBL/R1 are crucial regulators of β-cell identity and determinants of diabetes development and progression

  pancreatic fed paraffin-embedded pancreas qpcr blood oral

• MYC-induced USP10 stabilizes SOX4 to promote thymocyte proliferation and leukemia onset in mice.

  PMID 41927540 · PMC13216311 · Nature communications · 2026 · 8 claims · 8 setups

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  USP10 is dynamically expressed in thymocytes, peaking during proliferative stages of T cell development in both mouse and human

  thymocytes thymocyte t-all lin dub rt-qpcr single-cell