Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Regulation of P2X2 receptors by the neuronal calcium sensor VILIP1.
PMID 18922787 · PMC3523710 · Science signaling · 2008 · 8 claims · 8 setups
VILIP1 was identified via a proteomic (GST pull-down) approach as a protein interacting with the P2X2 receptor C-terminal tail
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Prioritization of candidate cancer genes--an aid to oncogenomic studies.
PMID 18710882 · PMC2566894 · Nucleic acids research · 2008 · 8 claims · 8 setups
Computational classifiers using combinations of protein conservation, gene structure, protein domains, protein interactions, and regulatory data can distinguish known cancer genes (CD/CR) from unlabelled human genes
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A virtual computer lab for distance biomedical technology education.
PMID 18366629 · PMC2292716 · BMC medical education · 2008 · 6 claims · 4 setups
A 'virtual computer lab' combining videoconferencing with VNC-based desktop sharing can replicate the functionality of a physical computer lab for distance biomedical technology education
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Evolutionary trace annotation of protein function in the structural proteome.
PMID 20036248 · PMC2831211 · Journal of molecular biology · 2010 · 8 claims · 7 setups
ET-ranked residue clusters can be used to build 3D templates that predict GO function in enzymes and non-enzymes alike, without prior knowledge of functional mechanism.
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Systems biology in human health and disease.
PMID 17893698 · PMC2013921 · Molecular systems biology · 2007 · 8 claims · 5 setups
High-throughput quantitative proteomics of signaling networks (e.g., HER2 overexpression) can be correlated with biological responses like proliferation and migration to better understand pathways deregulated in cancer.
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A computational study of off-target effects of RNA interference.
PMID 15800213 · PMC1072799 · Nucleic acids research · 2005 · 8 claims · 5 setups
The chance of RNAi off-target effects is considerable, ranging from 5% to 80% depending on organism and parameters, when using exact sequence identity between siRNA and transcripts.
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Has reproduction · 43
StatsDB: platform-agnostic storage and understanding of next generation sequencing run metrics.
PMID 24627795 · PMC3938176 · F1000Research · 2013 · 8 claims · 6 setups
StatsDB is an open-source software package for storage and analysis of next generation sequencing run metrics, backed by an SQL (MySQL) database with Perl and Java APIs.
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The genome of Brugia malayi - all worms are not created equal.
PMID 18952001 · PMC2668601 · Parasitology international · 2009 · 8 claims · 8 setups
Comparative genome analysis shows conserved long-range synteny but divergent local gene order between B. malayi and C. elegans, reflecting distinct evolutionary trajectories of parasitic and free-living lineages.