Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Multiomic and functional validation of ACSL3, a regulator of fatty acid metabolism, as a lymph node metastasis-associated gene in lung adenocarcinoma.

  PMID 41998631 · PMC13261843 · Respiratory research · 2026 · 8 claims · 8 setups

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  A five-gene FAM-related risk signature (ACSL3, MCAT, NDUFAB1, OLAH, ACSL4)-derived FScore stratifies LUAD prognosis across multiple independent cohorts

  tcga-luad luad a549 lymphatic bulk scrna-seq spatial

• Multi-Omics reveals SPP1 + malignant and CXCR4(+) TAM crosstalk predicts immunotherapy response in lung adenocarcinoma.

  PMID 42045760 · PMC13187092 · Discover oncology · 2026 · 8 claims · 8 setups

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  SPP1+ malignant and CXCR4+ TAM crosstalk drives CD8 T cell exhaustion and induces poor immunotherapy response

  luad tcga-luad epithelial a549 single-cell spatial bulk

• Downregulation of Splicing Factor PTBP1 Curtails FBXO5 Expression to Promote Cellular Senescence in Lung Adenocarcinoma.

  PMID 39057099 · PMC11276454 · Current issues in molecular biology · 2024 · 8 claims · 8 setups

  Has reproduction · 59

  PTBP1 is significantly upregulated across multiple cancer types including LUAD, and higher PTBP1 levels are associated with worse LUAD patient survival

  cancer luad fibroblast a549 pan-cancer differential replicative