Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Oxidized LDL Induces Pro-Inflammatory Transcriptomic and Epigenomic Responses in Human CD4(+) T Cells.

  PMID 41707046 · PMC12916081 · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026 · 8 claims · 6 setups

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  Ox-LDL causes a shift toward a pro-inflammatory, cytokine-producing transcriptomic state in activated CD4+ T cells

  activated naïve cd4+ cad rna-sequencing atac-sequencing chip-sequencing

• The AICL-KLRF1 axis supports CD4-CD8 T cell communication and cytokine competence in pre-exhausted CD8(+) T cells.

  PMID 41851343 · PMC13121605 · EMBO reports · 2026 · 8 claims · 8 setups

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  Progressive expression of KLRB1, KLRG1, GPR56, and KLRF1 tracks CD8+ T cell differentiation stages (TN, TCM, TEM, TEMRA), mirroring the pattern previously shown in CD4+ T cells

  unstimulated cd3+-enriched enriched cd8+ flow sorting-based spatial

• Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine-Dependent Pro-Inflammatory Immune Microenvironment.

  PMID 41580972 · PMC13042394 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · 8 claims · 8 setups

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  T cell-specific Socs1 loss intrinsically drives pro-inflammatory T cell differentiation independent of antigen stimulation, with the strongest effects in CD8+ T cells

  cd45+ splenic cd8+ sorted single-cell flow bulk

• Chemotherapy-induced reactive myelopoiesis promotes expansion of immunosuppressive neutrophil-like monocytes in mice and humans.

  PMID 41945895 · PMC13232731 · JCI insight · 2026 · 8 claims · 8 setups

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  Monocytes from lymphoma patients receiving CTX-containing chemotherapy show variable, often chemotherapy-induced or -enhanced, immunosuppressive activity against T cells

  pbmcs bone sorted facs-sorted scrna-seq flow atac-seq