Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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RB loss modulates chromatin organization by regulating cohesin-dependent loops and enhancer-promoter interactions.
PMID 41951674 · PMC13103356 · Nature communications · 2026 · 8 claims · 8 setups
RB colocalizes extensively with cohesin (SMC3) genome-wide, especially at insulators
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STAG2 loss amplifies EWS-FLI1-driven microsatellite enhancer activity promoting Ewing sarcoma aggressiveness.
PMID 41950086 · PMC13079922 · Proceedings of the National Academy of Sciences of the United States of America · 2026 · 8 claims · 8 setups
STAG2 loss does not globally attenuate EWS-FLI1 activity but reprograms its chromatin binding, redirecting it from short (1-4x) GGAA-repeat sites toward long/multimeric (≥5x) GGAA-repeat microsatellite enhancers
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Wnt-presenting materials sustain H3K14-acetylation in human skeletal stem cells for tissue engineering and bone repair.
PMID 41844625 · PMC13250124 · NPJ Regenerative medicine · 2026 · 8 claims · 8 setups
Localized Wnt3a signaling asymmetrically distributes H3K14ac between daughter cells during hSSC asymmetric cell division (ACD), with the Wnt-proximal cell retaining high H3K14ac and higher transcriptional activity (RNApolS2P)
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HIF sustain a transcriptional regulatory circuit of EPAS1 expression in renal clear cell carcinoma.
PMID 41714613 · PMC12921326 · Nature communications · 2026 · 8 claims · 8 setups
HIF-2α mRNA is specifically overexpressed in ccRCC tumor tissue/cells compared to normal kidney, while it is reduced in papillary and chromophobe RCC