Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Autoantibody profiling for the study and treatment of autoimmune disease.
PMID 12223102 · PMC128938 · Arthritis research · 2002 · 8 claims · 8 setups
Custom-fabricated antigen microarrays (spotted on poly-L-lysine-coated glass slides) enable multiplex profiling of autoantibody responses in autoimmune disease sera.
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Causes of early-onset type 1 diabetes: toward data-driven environmental approaches.
PMID 19075294 · PMC2605242 · The Journal of experimental medicine · 2008 · 8 claims · 1 setups
Serum metabolite profiling reveals metabolic changes that precede islet autoantibody appearance and predict which children will develop T1D
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SePaCS--a web-based application for classification of seroreactivity profiles.
PMID 17478503 · PMC1933220 · Nucleic acids research · 2007 · 8 claims · 4 setups
SePaCS is a freely available web-based tool that trains and applies multiple classification methods (4 Naive Bayes variants, SVM with RBF kernel, LDA, DLDA) to seroreactivity profiles and outputs results as a summary table plus a detailed PDF report
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Resistance to thyroid hormone with missense mutation (V349M) in the thyroid hormone receptor beta gene.
PMID 18363280 · PMC2686955 · The Korean journal of internal medicine · 2008 · 8 claims · 7 setups
The patient's resistance to thyroid hormone (RTH) was caused by a novel missense mutation (V349M, c.1045G>A) in exon 11 of the TRβ gene, the first such case reported in Korea.
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Comprehensive phenotyping in multiple sclerosis: discovery based proteomics and the current understanding of putative biomarkers.
PMID 17124343 · PMC3851054 · Disease markers · 2006 · 8 claims · 8 setups
No single diagnostic test exists for MS; diagnosis relies on clinical evaluation, MRI abnormalities, and CSF chemistry
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A new form of diabetes caused by INS mutations defined by zygosity, stem cell and population data.
PMID 41484206 · PMC12905373 · EMBO molecular medicine · 2026 · 6 claims · 7 setups
INS R6C is a recessive loss-of-function mutation causing diabetes only in homozygous individuals, not a dominant mutation as previously classified.
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Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach.
PMID 17125526 · PMC1794520 · Arthritis research & therapy · 2006 · 8 claims · 6 setups
51 citrullinated protein spots were detected in RA synovial tissue, of which 30 (58.8%) were autoantigenic (reactive with RA sera)
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Tipping the balance in autoimmune disease.
PMID 18001485 · PMC2246277 · Genome biology · 2007 · 8 claims · 8 setups
Human autoimmune diseases are fundamentally diseases of immune dysfunction, evidenced by predisposing genes being immune-function genes, some shared and some unique across MS, T1D, SLE, CD and RA