Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Boosting accuracy of automated classification of fluorescence microscope images for location proteomics.
PMID 15207009 · PMC449699 · BMC bioinformatics · 2004 · 8 claims · 8 setups
New classifiers (SVMs, ensembles) and new wavelet-derived (Gabor, Daubechies) features improve recognition of protein subcellular location patterns over the previous neural network approach
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Has reproduction · 85
Ensembl 2013.
PMID 23203987 · PMC3531136 · Nucleic acids research · 2013 · 8 claims · 8 setups
Ensembl (http://www.ensembl.org) provides genome information for sequenced chordate genomes, currently supporting 70 species with a focus on human, mouse, zebrafish and rat.
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GeneKeyDB: a lightweight, gene-centric, relational database to support data mining environments.
PMID 15790402 · PMC1274265 · BMC bioinformatics · 2005 · 8 claims · 6 setups
GeneKeyDB is a lightweight, gene-centric relational database that supports data mining and integration with computational analysis tools.
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VectorBase: a home for invertebrate vectors of human pathogens.
PMID 17145709 · PMC1751530 · Nucleic acids research · 2007 · 8 claims · 5 setups
VectorBase is a web-accessible data repository for information about invertebrate vectors of human pathogens
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MBGD update 2010: toward a comprehensive resource for exploring microbial genome diversity.
PMID 19906735 · PMC2808943 · Nucleic acids research · 2010 · 8 claims · 6 setups
MBGD allows users to create ortholog groups using a specified subgroup of organisms, distinguishing it from other comparative genomics resources
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Structural evolution of the protein kinase-like superfamily.
PMID 16244704 · PMC1261164 · PLoS computational biology · 2005 · 8 claims · 5 setups
All kinases in the superfamily share a 'universal core' domain consisting only of the regions required for ATP binding and the phosphotransfer reaction.
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Has reproduction · 60
Deconvolution of the hematopoietic stem cell microenvironment reveals a high degree of specialization and conservation.
PMID 35494238 · PMC9046238 · iScience · 2022 · 8 claims · 6 setups
A customized bootstrapping/random-forest divide-and-conquer clustering pipeline integrating three scRNA-seq datasets robustly resolves cell states despite high cell-to-cell similarity within compartments
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Connecting synthetic chemistry decisions to cell and genome biology using small-molecule phenotypic profiling.
PMID 19825513 · PMC2787914 · Current opinion in chemical biology · 2009 · 8 claims · 8 setups
Multidimensional phenotypic profiling leverages information content from multiple parallel or multiplexed measurements of compound action on cells, unlike hierarchical screening which filters to few 'interesting' compounds.