Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• RANKL inhibits macrophage proinflammatory Toll-like receptor 2 and 4 signaling and impairs killing of intracellular bacteria.

  PMID 42177796 · PMC13198865 · ImmunoHorizons · 2026 · 8 claims · 8 setups

  Full-text index only

  Prior RANKL exposure increases intracellular Salmonella Typhimurium (STm) burden in mouse and human macrophages

  bone bmdms raw-dual splenic bacterial viability sequencing

• Bacterial reporter-paired scRNA sequencing reveals cross talk between zinc starvation and zinc toxicity in macrophage antibacterial defense.

  PMID 41802048 · PMC12993976 · Proceedings of the National Academy of Sciences of the United States of America · 2026 · 8 claims · 8 setups

  Full-text index only

  Macrophages starve intracellular E. coli of zinc to sensitize them to subsequent zinc toxicity, coupling zinc starvation and zinc toxicity in a single antimicrobial response

  monocyte-derived hmdm zntr-dual macrophages confocal high-throughput flow

• Single-cell analysis of testicular bacterial microbiome changes during aging and effect on reproductive capacity in mice.

  PMID 41438041 · PMC12719757 · iScience · 2025 · 8 claims · 8 setups

  Has reproduction · 78

  INVADE-seq (single-cell RNA-seq combined with 16S rRNA targeting) detects a sparse but widespread bacterial presence across diverse testicular cell types

  testis young testicular invade-seq histology sperm

• Bioengineering a humanized acne microenvironment model: proteomics analysis of host responses to Propionibacterium acnes infection in vivo.

  PMID 18651708 · PMC2699546 · Proteomics · 2008 · 8 claims · 6 setups

  Full-text index only

  A dermis-based cell-trapped system (DBCTS) with human sebocytes inserted into a subcutaneous tissue chamber creates a humanized acne microenvironment in mice

  chamber infiltrated de-epidermized sebocyte cfu sandwich immunofluorescence

• Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology.

  PMID 41489684 · PMC12767585 · The Journal of experimental medicine · 2026 · 8 claims · 8 setups

  Full-text index only

  MMP1+CXCL5+ fibroblasts and SPP1+ macrophages are linked to TB disease and TB lung granuloma and reveal targetable cellular cross talk underlying TB immunopathology

  lung ffpe lymph nonhuman scrna-seq spatial bulk