Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Seasonal Dynamics Are the Major Driver of Microbial Diversity and Composition in Intensive Freshwater Aquaculture.
PMID 34248892 · PMC8264503 · Frontiers in microbiology · 2021 · 7 claims · 6 setups
Natural seasonality is the primary driver of aquatic bacterial community structure in the fishponds and reservoir
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Has reproduction · 69
High-resolution metagenomic reconstruction of the freshwater spring bloom.
PMID 36698172 · PMC9878933 · Microbiome · 2023 · 8 claims · 8 setups
High-frequency metagenomic sampling (57 samples, 3 filter sizes, 2 depths, 37 days) recovers thousands of prokaryotic, eukaryotic, and viral genomes tracking spring bloom succession in fine detail
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Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes.
PMID 17916580 · PMC2533590 · DNA research : an international journal for rapid publication of reports on genes and genomes · 2007 · 7 claims · 7 setups
Adult and weaned-children gut microbiota show high functional (gene-content) uniformity despite taxonomic differences, while unweaned infant microbiota show high inter-individual variation in both taxonomic and gene composition.
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Has reproduction · 62
The soil microbiome modulates the sorghum root metabolome and cellular traits with a concomitant reduction of Striga infection.
PMID 38537644 · PMC11063626 · Cell reports · 2024 · 8 claims · 8 setups
The natural (non-sterilized) Clue Field soil microbiome reduces Striga attachment to sorghum roots compared to gamma-sterilized soil
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BaGPipe: an automated, reproducible, and flexible pipeline for bacterial genome-wide association studies.
PMID 41896736 · PMC13147680 · BMC microbiology · 2026 · 7 claims · 8 setups
BaGPipe is an automated, reproducible Nextflow pipeline that integrates pre-processing, Pyseer-based association analysis, and downstream visualisation into a unified bacterial GWAS workflow
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Has reproduction · 44
An OMICs-based meta-analysis to support infection state stratification.
PMID 33560295 · PMC8388022 · Bioinformatics (Oxford, England) · 2021 · 7 claims · 6 setups
Multi-class Random Forest models built from meta-analyzed blood gene expression data can predict infection state (bacterial/viral/none) with high accuracy, correctly classifying 93% of bacterial and 89% of viral samples in the best model.
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Has reproduction · 94
A four-gene signature from blood to exclude bacterial etiology of lower respiratory tract infection in adults.
PMID 41285807 · PMC12644739 · Nature communications · 2025 · 8 claims · 8 setups
A 4-gene signature (ITGB4, ITGA7, IFI27, FAM20A) derived from whole blood RNA-seq discriminates any bacterial from nonbacterial ARI with cross-validated AUC = 0.90
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Large-scale estimation of bacterial and archaeal DNA prevalence in metagenomes reveals biome-specific patterns.
PMID 41854267 · PMC13098197 · mSystems · 2026 · 8 claims · 6 setups
SPF scalably and robustly estimates the fraction of bacterial and archaeal reads in a metagenome using detection of prokaryotic single-copy marker genes, without requiring eukaryotic or viral reference genomes
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Has reproduction · 32
Identifying COVID-19-Specific Transcriptomic Biomarkers with Machine Learning Methods.
PMID 34307679 · PMC8272456 · BioMed research international · 2021 · 7 claims · 2 setups
A pipeline combining Boruta and mRMR feature selection with incremental feature selection (IFS) was used to identify COVID-19-specific transcriptomic biomarkers from blood gene expression data.
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Has reproduction · 39
Glacier shrinkage will accelerate downstream decomposition of organic matter and alters microbiome structure and function.
PMID 35320603 · PMC9323552 · Global change biology · 2022 · 8 claims · 7 setups
Glacier shrinkage (decreasing glacier influence) accelerates downstream organic matter decomposition rates in glacier-fed streams
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Has reproduction · 55
Environment and Co-occurring Native Mussel Species, but Not Host Genetics, Impact the Microbiome of a Freshwater Invasive Species (Corbicula fluminea).
PMID 35444631 · PMC9014210 · Frontiers in microbiology · 2022 · 7 claims · 7 setups
The gut microbiome of C. fluminea is diverse, differs with environmental conditions, and varies spatially among rivers, but is unrelated to host genetic variation
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Has reproduction · 75
Different Intestinal Microbiota with Growth Stages of Three-Breed Hybrid Pig.
PMID 35978648 · PMC9377885 · BioMed research international · 2022 · 7 claims · 5 setups
The composition and relative abundance of intestinal microbiota in three-breed hybrid pigs differ significantly across growth stages (60, 120, 180 days)
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Dynamics of gut bacteriophage in diversity outbred mice studied over lifespan and during extreme caloric restriction.
PMID 41772715 · PMC12983593 · Microbiome · 2026 · 8 claims · 8 setups
Quiescent prophages dominate gut viral metagenomes, consistent with 'piggyback-the-winner' dynamics
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Antimicrobial resistance dissemination via horizontal gene transfer is constrained in stratified waters.
PMID 41813906 · PMC13022341 · Communications biology · 2026 · 8 claims · 7 setups
No evidence for recent HGT-mediated dissemination of ARGs across depth layers was detected, despite genetic compatibility among co-occurring bacteria.
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Has reproduction · 98
Mutations in dnaA and a cryptic interaction site increase drug resistance in Mycobacterium tuberculosis.
PMID 33253310 · PMC7738170 · PLoS pathogens · 2020 · 7 claims · 8 setups
Non-synonymous mutations in dnaA are statistically associated with drug resistance (INH, RIF, SM) in clinical M. tuberculosis strains across two independent GWAS cohorts (China and Vietnam)