Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Computer-aided identification of polymorphism sets diagnostic for groups of bacterial and viral genetic variants.
PMID 17672919 · PMC1973086 · BMC bioinformatics · 2007 · 6 claims · 8 setups
The Not-N algorithm, incorporated into the Minimum SNPs program, identifies small marker sets diagnostic for user-defined subgroups of genetic variants with 0% false negatives
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Has reproduction · 50
BiRNA-BERT allows efficient RNA language modeling with adaptive tokenization.
PMID 41266599 · PMC12635123 · Communications biology · 2025 · 8 claims · 8 setups
BiRNA-BERT uses adaptive dual-tokenization that dynamically selects nucleotide-level (NUC) or byte-pair encoding (BPE) tokens based on input sequence length
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MODBASE: a database of annotated comparative protein structure models and associated resources.
PMID 16381869 · PMC1347422 · Nucleic acids research · 2006 · 8 claims · 7 setups
MODBASE is a database of automatically calculated comparative protein structure models covering all UniProt sequences matchable to a known structure
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MODBASE, a database of annotated comparative protein structure models and associated resources.
PMID 18948282 · PMC2686492 · Nucleic acids research · 2009 · 8 claims · 8 setups
MODBASE contains 5,152,695 reliable comparative protein structure models for 1,593,209 unique protein sequences.
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The European Bioinformatics Institute's data resources: towards systems biology.
PMID 15608238 · PMC539980 · Nucleic acids research · 2005 · 8 claims · 5 setups
Since 2003 the EBI has launched new databases covering protein-protein interactions (IntAct), pathways (Reactome) and small molecules (ChEBI)
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Ab initio identification of human microRNAs based on structure motifs.
PMID 18088431 · PMC2238772 · BMC bioinformatics · 2007 · 8 claims · 7 setups
MiRPred predicts miRNA precursors ab initio using only predicted secondary structure motifs, ignoring nucleotide sequence
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SNAP predicts effect of mutations on protein function.
PMID 18757876 · PMC2562009 · Bioinformatics (Oxford, England) · 2008 · 8 claims · 3 setups
SNAP is a publicly available web-server implementation predicting functional effects (neutral/non-neutral) of single amino acid substitutions.
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Has reproduction · 83
Macrel: antimicrobial peptide screening in genomes and metagenomes.
PMID 33384902 · PMC7751412 · PeerJ · 2020 · 8 claims · 8 setups
Macrel is an end-to-end pipeline that predicts high-quality AMP candidates from peptides, contigs, or reads of (meta)genomes
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Has reproduction · 67
Adaptive learning embedding features to improve the predictive performance of SARS-CoV-2 phosphorylation sites.
PMID 37847658 · PMC10628388 · Bioinformatics (Oxford, England) · 2023 · 7 claims · 3 setups
PSPred-ALE, a deep learning predictor using a self-adaptive learning embedding algorithm, automatically extracts contextual sequence features and identifies SARS-CoV-2 phosphorylation sites without feature engineering.
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Has reproduction · 89
MirDIP 5.2: tissue context annotation and novel microRNA curation.
PMID 36453996 · PMC9825511 · Nucleic acids research · 2023 · 7 claims · 6 setups
mirDIP 5.2 removed eight outdated resources, added miRNATIP, and ran five prediction algorithms against miRBase and mirGeneDB miRNAs to expand and improve interaction coverage
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Automatic discovery of cross-family sequence features associated with protein function.
PMID 16409628 · PMC1395344 · BMC bioinformatics · 2006 · 8 claims · 6 setups
A self-supervised data mining approach can find relationships between sequence features and functional annotations without preconceived functional categories.