Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Inferring combinatorial regulation of transcription in silico.
PMID 15647509 · PMC546154 · Nucleic acids research · 2005 · 8 claims · 5 setups
Combining Cluster-Buster (TFBS cluster prediction) with GOSSIP (rigorous GO enrichment statistics with multiple-testing/FDR correction) predicts biological functions controlled by combinatorial transcription factor action, without prior knowledge of factor targets
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Web services and workflow management for biological resources.
PMID 16351751 · PMC1866383 · BMC bioinformatics · 2005 · 8 claims · 4 setups
Workflow management systems combined with Web Services are a promising ICT approach for automating access to and integration of biomedical data.
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Of mice and men: comparative proteomics of bronchoalveolar fluid.
PMID 20032019 · PMC3049194 · The European respiratory journal · 2010 · 8 claims · 8 setups
Comparative shotgun proteomics of human and mouse BALF identifies conserved pathways (immunity, defence response, protease activity) alongside species-specific divergent pathways.
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Sys-BodyFluid: a systematical database for human body fluid proteome research.
PMID 18978022 · PMC2686600 · Nucleic acids research · 2009 · 6 claims · 4 setups
Sys-BodyFluid is a web-based database integrating proteomic data from 11 human body fluids (plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar lavage fluid, synovial fluid, nipple aspirate fluid, tear fluid, seminal fluid, milk, amniotic fluid), containing over 10,000 proteins
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A proteomics grade electron transfer dissociation-enabled hybrid linear ion trap-orbitrap mass spectrometer.
PMID 18613715 · PMC2601597 · Journal of proteome research · 2008 · 8 claims · 5 setups
A NCI source coupled via an added octopole and the c-trap to a QLT-orbitrap enables fast, efficient ETD reagent anion injection (4-8 ms)
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Has reproduction · 86
Molecular Classification Models for Triple Negative Breast Cancer Subtype Using Machine Learning.
PMID 34575658 · PMC8472680 · Journal of personalized medicine · 2021 · 6 claims · 4 setups
A training gene set of 719 unique upregulated DEGs (subtype-specific) can be used to build ML models that classify TNBC into BLIA, BLIS, MES, and LAR subtypes.
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Has reproduction · 83
Public Omics Explorer (POE): Enabling integrative semantic search across GEO omics datasets based on PubMed publications.
PMID 41282419 · PMC12636342 · Computational and structural biotechnology journal · 2025 · 6 claims · 4 setups
POE is a web platform that semantically links GEO datasets and ENA records through their associated PubMed publications for literature-informed dataset retrieval
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Genome-wide analysis of small RNA and novel MicroRNA discovery in human acute lymphoblastic leukemia based on extensive sequencing approach.
PMID 19724645 · PMC2731166 · PloS one · 2009 · 7 claims · 5 setups
159 novel miRNAs and 116 novel miRNA*s were identified from ALL patient and normal donor small RNA libraries
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Has reproduction · 75
Identification of Key Differentially Expressed Genes in Arabidopsis thaliana Under Short- and Long-Term High Light Stress.
PMID 40869111 · PMC12386182 · International journal of molecular sciences · 2025 · 7 claims · 5 setups
Short- and long-term HL responses in Arabidopsis leaves are driven by distinct transcriptional programs, with duration of HL treatment as the primary factor separating transcriptomic clusters.
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Decision tree-driven tandem mass spectrometry for shotgun proteomics.
PMID 18931669 · PMC2597439 · Nature methods · 2008 · 8 claims · 5 setups
A decision tree (DT) algorithm that selects CAD or ETD per precursor based on z and m/z yields more peptide identifications than either CAD or ETD alone
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Has reproduction · 61
Comprehensive transcriptome study to develop molecular resources of the copepod Calanus sinicus for their potential ecological applications.
PMID 24982883 · PMC4055022 · BioMed research international · 2014 · 8 claims · 8 setups
Illumina RNA-Seq with Trinity de novo assembly produced a C. sinicus transcriptome of 69,751 contigs (average 928.8 bp, N50 1,127 bp) from 58.9 million reads.
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Proteomic-based identification of maternal proteins in mature mouse oocytes.
PMID 19646285 · PMC2730056 · BMC genomics · 2009 · 8 claims · 6 setups
625 different proteins were identified from 2700 zona pellucida-free mature mouse MII oocytes, the largest oocyte proteome catalog to date
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Information extraction from full text scientific articles: where are the keywords?
PMID 12775220 · PMC166134 · BMC bioinformatics · 2003 · 8 claims · 5 setups
The keyword content of the five article sections (A, I, M, R, D) is heterogeneous, i.e., different sections carry different kinds of information.
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Identifying the important HIV-1 recombination breakpoints.
PMID 18787691 · PMC2522274 · PLoS computational biology · 2008 · 8 claims · 3 setups
Local sequence identity between co-packaged parental RNAs strongly influences the probability of strand-transfer/breakpoint location, with fewer breakpoints occurring near mismatches