Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Cancer screening: a mathematical model relating secreted blood biomarker levels to tumor sizes.
PMID 18715113 · PMC2517618 · PLoS medicine · 2008 · 8 claims · 4 setups
A linear one-compartment mathematical model can relate secreted blood tumor biomarker levels to tumor burden/size at steady state
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Has reproduction · 62
scATD: a high-throughput and interpretable framework for single-cell cancer drug resistance prediction and biomarker identification.
PMID 40501071 · PMC12159290 · Briefings in bioinformatics · 2025 · 8 claims · 6 setups
scATD enables high-throughput single-cell drug sensitivity prediction for new patients without model parameter retraining via bidirectional Bi-AdaIN style transfer
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The proteogenomic path towards biomarker discovery.
PMID 18764911 · PMC2574627 · Pediatric transplantation · 2008 · 8 claims · 8 setups
Serum creatinine is a widely used but non-ideal biomarker for renal transplant monitoring because it lacks specificity and sensitivity for graft injury
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A new era for proteomics research?
PMID 19014405 · PMC2614486 · Genome biology · 2008 · 8 claims · 8 setups
Refined mass spectrometry instrumentation and software now make whole-proteome coverage of model organisms in a single experiment conceivable
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Expanding the vision of environmental health at UNC-CH.
PMID 15248304 · PMC1247395 · Environmental health perspectives · 2004 · 8 claims · 8 setups
Human breast tumors arise from at least two distinct cell types, basal and luminal epithelial, with different clinical behavior
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Application of proteomics in the study of tumor metastasis.
PMID 15862116 · PMC5172469 · Genomics, proteomics & bioinformatics · 2004 · 8 claims · 8 setups
Cell function is directly regulated through proteins, not genes or mRNA, so metastasis-related gene findings need protein-level validation via proteomics.
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Improvements to cardiovascular gene ontology.
PMID 19046747 · PMC2706316 · Atherosclerosis · 2009 · 8 claims · 8 setups
Gene Ontology (GO) provides a controlled vocabulary that links current functional knowledge of genes to high-throughput genomic and proteomic datasets, aiding data interpretation.
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Has reproduction · 49
Integrative transcriptomics and single-cell transcriptomics analyses reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma.
PMID 40520228 · PMC12162626 · Frontiers in genetics · 2025 · 8 claims · 8 setups
ENTPD1, SERPINA1, and TACSTD2 are potential transcriptomic biomarkers for PTC
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The use of laser capture microscopy in proteomics research--a review.
PMID 15502248 · PMC3839334 · Disease markers · 2004 · 8 claims · 8 setups
LCM allows purification of specific, histologically defined cell populations from heterogeneous tissue for downstream proteomic analysis
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New perspectives on an old disease: proteomics in cancer research.
PMID 17472735 · PMC1895992 · Genome biology · 2007 · 8 claims · 8 setups
The HUPO Plasma Proteome Project has catalogued over 3,020 non-redundant gene products (>7,000 proteins/isoforms) in human plasma, many originating from tissues/organs rather than being plasma-intrinsic.
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Glycomics and disease markers.
PMID 19775929 · PMC2788081 · Current opinion in chemical biology · 2009 · 8 claims · 7 setups
Over 70% of all human proteins are glycosylated
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Report of the 9th HLPP Workshop October 2007, Seoul, Korea.
PMID 18683817 · PMC4601560 · Proteomics · 2008 · 8 claims · 8 setups
An integrated separating-identifying platform identified 6788 proteins (≥2 peptides, 95% confidence) in Chinese human liver samples, including 3721 new to liver and 977 hypothetical proteins