Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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A biomarker panel for peripheral arterial disease.
PMID 18687758 · PMC3133945 · Vascular medicine (London, England) · 2008 · 7 claims · 6 setups
β2-microglobulin (β2M) and cystatin C had the highest correlation with ABI among all plasma markers tested, higher than age, smoking, or diabetes status
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Mass spectrometry-based biomarker discovery: toward a global proteome index of individuality.
PMID 20636062 · PMC3140421 · Annual review of analytical chemistry (Palo Alto, Calif.) · 2009 · 8 claims · 4 setups
Very few large-scale longitudinal MS-based proteomics studies have been performed to establish analytical variability relative to true biological variability.
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Multimodal techniques for diagnosis and prognosis of Alzheimer's disease.
PMID 19829371 · PMC2810658 · Nature · 2009 · 8 claims · 8 setups
AD pathology accumulates for approximately 10-15 years in a preclinical phase before synaptic and neuronal loss manifest as cognitive decline
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The process chain for peptidomic biomarker discovery.
PMID 16410650 · PMC3850862 · Disease markers · 2006 · 8 claims · 3 setups
Peptidomics (comprehensive analysis of peptides and small proteins <20 kDa) fills a methodological gap left by standard proteomics, which mainly addresses proteins in the ~10-200 kDa range.
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Identification of serum biomarkers for colon cancer by proteomic analysis.
PMID 16755300 · PMC2361335 · British journal of cancer · 2006 · 8 claims · 8 setups
Complement C3a des-arg, α1-antitrypsin and transferrin were identified as serum proteins with diagnostic potential for CRC.
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A mouse to human search for plasma proteome changes associated with pancreatic tumor development.
PMID 18547137 · PMC2504036 · PLoS medicine · 2008 · 7 claims · 8 setups
GEM models combined with in-depth proteomic analysis provide a useful strategy to identify candidate cancer markers applicable to human disease with potential for early detection