Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• A stem and progenitor cell-derived gene expression signature is prognostic for survival in myelofibrosis.

  PMID 41481381 · PMC13155955 · Blood · 2026 · 8 claims · 4 setups

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  A 24-gene HSPC-derived weighted-sum expression score (MPN24) is prognostic for overall survival in myelofibrosis

  peripheral lin-cd34+ pb-mncs pm-c1 bulk single-cell nanostring

• RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia.

  PMID 39820365 · PMC11739599 · Nature communications · 2025 · 8 claims · 8 setups

  Has reproduction · 73

  RSK1 is a conserved, exploitable therapeutic dependency across MPN and secondary AML

  sorted mpn cd34+ aml bulk targeted mass

• Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow.

  PMID 42043300 · PMC13120821 · eLife · 2026 · 8 claims · 8 setups

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  Adult bone marrow-resident Cdh5/VE-Cadherin+ endothelial cells produce hematopoietic cell progeny both in vitro and in vivo.

  bone lin sorted lethally flow confocal sorted-cell

• Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation.

  PMID 41477881 · PMC12850507 · Science (New York, N.Y.) · 2026 · 8 claims · 8 setups

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  A haplotype at the 17q22 locus, tagged by the noncoding variant rs17834140-T, is a causal protective variant against CHIP and myeloid malignancies

  population hspcs cd34+cd45ra-cd90+ heterozygous gwas atac-seq crispr