Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: serum ✕ Assay: blue ✕ Clear

Heart disease, clinical proteomics and mass spectrometry.

PMID 15502250 · PMC3839266 · Disease markers · 2004 · 8 claims · 4 setups

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Proteins bound to serum albumin (the albuminome) will be altered in patients with heart failure compared to controls

swine animal general affinity maldi-tof tandem
Proteomic-based identification of haptoglobin-1 precursor as a novel circulating biomarker of ovarian cancer.

PMID 15199385 · PMC2364749 · British journal of cancer · 2004 · 7 claims · 7 setups

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Six serum protein spots (~40 kDa, pI 5.9–6.6) significantly overexpressed in grade 1, 2 and 3 ovarian cancer patients were identified by MALDI-TOFMS and n-ESIQ(q)TOFMS as isoforms of haptoglobin-1 precursor (HAP1)

serum tryptic 2de-separated paraffin-embedded two-dimensional affi-gel maldi-tofms
A high-temporal resolution technology for dynamic proteomic analysis based on 35S labeling.

PMID 18714357 · PMC2500177 · PloS one · 2008 · 6 claims · 6 setups

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35S pulse-labeling (phosphor-imaging) detects more protein spots with higher sensitivity than CBB staining on the same 2-DE gels

a549 liver 35s electrophoresis paired
Proteomic studies of cholangiocarcinoma and hepatocellular carcinoma cell secretomes.

PMID 20069059 · PMC2801507 · Journal of biomedicine & biotechnology · 2010 · 7 claims · 5 setups

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The secretomes of cholangiocarcinoma (HuCCA-1) and four hepatocellular carcinoma cell lines show distinct, differing protein profiles.

hucca-1 same conditioned paired sds-page trypan 1-de
A novel peak detection approach with chemical noise removal using short-time FFT for prOTOF MS data.

PMID 19681055 · PMC2782493 · Proteomics · 2009 · 8 claims · 2 setups

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PDA_stFFT is a novel automatic peak detection method for prOTOF MS data that does not require a priori knowledge of protein masses

peptide serum maldi-tof
Comprehensive bioinformatics analysis and experimental verification identify mitochondrial gene Dgat2 as a novel therapeutic biomarker for myocardial ischemia-reperfusion.

PMID 40510478 · PMC12159077 · Frontiers in endocrinology · 2025 · 8 claims · 8 setups

Has reproduction · 64

Dgat2 is a hub mitochondria-related differentially expressed gene (MitoDEG) that can serve as a novel biomarker and therapeutic target in MI/RI

heart degs dgat2 mitodegs microarray kegg protein-protein

Experiments

Heart disease, clinical proteomics and mass spectrometry.

Proteomic-based identification of haptoglobin-1 precursor as a novel circulating biomarker of ovarian cancer.

A high-temporal resolution technology for dynamic proteomic analysis based on 35S labeling.

Proteomic studies of cholangiocarcinoma and hepatocellular carcinoma cell secretomes.

A novel peak detection approach with chemical noise removal using short-time FFT for prOTOF MS data.

Comprehensive bioinformatics analysis and experimental verification identify mitochondrial gene Dgat2 as a novel therapeutic biomarker for myocardial ischemia-reperfusion.