Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Comprehensive stage- and tissue-specific transcriptome of the global ecosystem service insect, marmalade hoverfly Episyrphus balteatus.

  PMID 41927565 · PMC13216633 · Scientific data · 2026 · 8 claims · 8 setups

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  Generated a comprehensive developmental- and tissue-resolved transcriptome dataset for Episyrphus balteatus as a community resource

  egg larva pupa antenna bulk

• De novo transcriptome assembly and comprehensive assessment provide insight into fruiting body formation of Sparassis latifolia.

  PMID 35773379 · PMC9247108 · Scientific reports · 2022 · 6 claims · 7 setups

  Has reproduction · 46

  De novo transcriptome assembly of S. latifolia produced 48,549 unigenes, 71.53% (34,728) of which were annotated against KEGG, GO, and/or KOG databases

  sparassis latifolia bulk transcriptome sequence

• High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA-tRNA interface.

  PMID 25122613 · PMC4216921 · Genome research · 2014 · 8 claims · 7 setups

  Has reproduction · 87

  mRNA codon and amino acid pools are highly stable across mouse development and across tissues, simply reflecting the genomic background distribution of any possible transcriptome.

  c57bl strand-specific pol computational

• Core transcriptional signatures of phase change in the migratory locust.

  PMID 31292921 · PMC6881432 · Protein & cell · 2019 · 8 claims · 7 setups

  Has reproduction · 60

  PhaseCore genes, identified via AC-PCA across developmental, tissue, and time-course datasets, predict locust phase status (gregarious vs. solitary) with over 87.5% accuracy

  locusta bulk interference transcriptional

• Genetic parallels in biomineralization of the calcareous sponge Sycon ciliatum and stony corals.

  PMID 40922549 · PMC12419799 · eLife · 2025 · 8 claims · 8 setups

  Has reproduction · 50

  829 genes are overexpressed in regions of increased calcite spicule formation in S. ciliatum, including known sclerocyte-specific biomineralization genes.

  sycon ciliatum cnidarian sponges differential go-term blastp

• Application of ecotoxicogenomics for studying endocrine disruption in vertebrates and invertebrates.

  PMID 16818254 · PMC1874166 · Environmental health perspectives · 2006 · 8 claims · 8 setups

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  Estrogen-responsive genes in mouse uterus are induced in a dose-dependent, ER-α-dependent manner, as shown by loss of induction in ER-α knockout mice.

  reproductive american xenopus fundulus cdna receptor developmental

• The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice.

  PMID 20368178 · PMC2894525 · Science translational medicine · 2009 · 7 claims · 6 setups

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  Germ-free C57BL/6J mice can be stably and heritably colonized with a human fecal microbiota, reproducing much of the donor's bacterial diversity.

  fecal postnatal luminal pooled 16s shotgun body

• Limited protection against early-life lung murine cytomegalovirus infection results from deficiency of cytotoxic CD8 T cells.

  PMID 42008567 · PMC13128127 · PLoS pathogens · 2026 · 9 claims · 9 setups

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  Expansion of endogenous MCMV-specific CD8 T cells is delayed in early life due to a low precursor frequency of peripheral αβ T cells

  peripheral spleen polyclonal neonatal pmhc-i mhc-ii flow

• PFOS and PFOA exposure induces liver injury and sex-dependent immune effects in C57BL/6 mice.

  PMID 41641100 · PMC12865548 · iScience · 2026 · 7 claims · 7 setups

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  PFOA and PFOS exposure induces hepatotoxicity, including hepatomegaly and elevated serum liver injury biomarkers (ALP, ALT), across sexes and durations

  plasma liver serum thymus lc-ms organ serum

• Vertebrate-wide transcriptomic screening identifies immune cell-specific expression of the conserved OR-κ gene.

  PMID 41654976 · PMC13113109 · Zoological letters · 2026 · 8 claims · 8 setups

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  The majority (95-97%) of chemoreceptor genes are expressed in nasal/oral chemosensory organs across mouse, Xenopus, Polypterus, and zebrafish

  mus zebrafish xenopus polypterus bulk single-cell molecular

• Lipids join the post-genomic era.

  PMID 17076911 · PMC1794566 · Genome biology · 2006 · 8 claims · 8 setups

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  Infrared-laser MALDI-MS can image biological tissue while avoiding the matrix-preparation artifacts of UV-laser MALDI

  biological intact mixtures yeast maldi esi faims

• TGFβ-activated PDHB promotes mitochondrial pyruvate metabolism and contributes to human endoderm differentiation via ATP-dependent BRG1.

  PMID 41702907 · PMC13022444 · Nature communications · 2026 · 8 claims · 8 setups

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  DE differentiation requires a TGFβ-driven metabolic switch characterized by reduced lactate production and enhanced TCA cycle activity/oxidative phosphorylation, mediated by PDHB

  escs crispr flow qrt-pcr