Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Single-cell analysis reveals multi-faceted features of B cell development, together with age-associated B cell subpopulations.

  PMID 41520091 · PMC12905261 · Communications biology · 2026 · 8 claims · 8 setups

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  18 B cell subpopulations were identified spanning the full developmental continuum from early progenitors to plasma cells, including 4 previously unappreciated minor subpopulations (FTLhi, S100A8hi immature; FOShi, HSPA1Ahi naïve).

  in-house enriched tonsil peripheral scrna-seq scvdj-seq velocity

• An Erg-driven transcriptional program controls B cell lymphopoiesis.

  PMID 32541654 · PMC7296042 · Nature communications · 2020 · 7 claims · 8 setups

  Has reproduction · 81

  Erg is essential for early B lymphoid differentiation

  erg b220+ prob wild-type lacz rna-seq flow

• MYC-induced USP10 stabilizes SOX4 to promote thymocyte proliferation and leukemia onset in mice.

  PMID 41927540 · PMC13216311 · Nature communications · 2026 · 8 claims · 8 setups

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  USP10 is dynamically expressed in thymocytes, peaking during proliferative stages of T cell development in both mouse and human

  thymocytes thymocyte t-all lin dub rt-qpcr single-cell

• Degeneration and adaptive evolution of digits in ratite birds.

  PMID 41982182 · PMC13135079 · Molecular biology and evolution · 2026 · 8 claims · 6 setups

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  Hindlimb digit 5 (HD5) degeneration shares 70-77% of candidate genes between ostrich and crocodile, indicating it originated once in the Archosauria stem lineage rather than independently.

  developing digit emu ostrich bulk alcian mount

• Distinct senotypes in p16- and p21-positive cells across human and mouse aging tissues.

  PMID 41162753 · PMC12669595 · The EMBO journal · 2025 · 7 claims · 8 setups

  Has reproduction · 50

  p16+ and p21+ senescent cells represent largely distinct, non-overlapping populations across murine and human aging tissues

  hippocampus brain skeletal bone scrna-seq cytof velocity

• Benchmarking RNA velocity methods across 17 independent studies.

  PMID 41916302 · PMC13106975 · Cell reports methods · 2026 · 8 claims · 6 setups

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  No single RNA velocity method exhibited superior performance across all accuracy, stability, and usability assessments

  scrna-seq same representative dyngen-simulated velocity cross-method downsampling

• Modular genetic architecture underlies human hand and foot evolution.

  PMID 42118837 · PMC13187773 · Proceedings of the National Academy of Sciences of the United States of America · 2026 · 8 claims · 8 setups

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  Gene expression and regulatory modules strongly separate metapodials from phalanges, and separate tissues to a lesser extent along the anterior-posterior axis or between limb types

  developing e15.5 chimpanzee developmental rna-seq atac-seq skeletal