Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Single-cell analysis reveals multi-faceted features of B cell development, together with age-associated B cell subpopulations.
PMID 41520091 · PMC12905261 · Communications biology · 2026 · 8 claims · 8 setups
18 B cell subpopulations were identified spanning the full developmental continuum from early progenitors to plasma cells, including 4 previously unappreciated minor subpopulations (FTLhi, S100A8hi immature; FOShi, HSPA1Ahi naïve).
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Has reproduction
Comprehensive analysis of m(6)A methylome alterations after azacytidine plus venetoclax treatment for acute myeloid leukemia by nanopore sequencing.
PMID 38510975 · PMC10950754 · Computational and structural biotechnology journal · 2024 · 8 claims · 6 setups
m6A site number and m6A levels are significantly lower in post-treatment complete remission (CR) bone marrow than in pre-treatment AML bone marrow
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Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma.
PMID 41364805 · PMC13012255 · Blood cancer discovery · 2026 · 7 claims · 8 setups
IFN-γ signaling after autologous stem cell transplant (ASCT) is associated with markers of impaired CD8+ T-cell memory phenotype
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PURE-seq integrates FACS and PIP-seq for single-cell genomics of ultra-rare cells.
PMID 41565684 · PMC12881479 · Nature communications · 2026 · 8 claims · 8 setups
PURE-seq integrates FACS sorting directly into PIP-seq barcoding reaction tubes, minimizing manual handling and cell loss for rare-cell single-cell sequencing.
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Has reproduction · 57
A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells.
PMID 34426512 · PMC8415381 · Genome research · 2021 · 8 claims · 8 setups
About 5% of tested PCRP antibodies showed high-confidence cognate-target enrichment in at least one assay and are strong candidates for further validation.
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Has reproduction · 50
Transcriptome profiling of osteoclast subsets associated with arthritis: A pathogenic role of CCR2(hi) osteoclast progenitors.
PMID 36591261 · PMC9797520 · Frontiers in immunology · 2022 · 8 claims · 6 setups
CCR2hi and CCR2lo periarticular bone marrow OCP subsets show a disparate transcriptome (863 differentially expressed genes)
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Multiomics combined drugs to explore the potential mechanism and treatment of ankylosing spondylitis.
PMID 41673882 · PMC13047816 · Journal of orthopaedic surgery and research · 2026 · 8 claims · 8 setups
Effector CD8+ memory T (Tem) cells are significantly elevated in AS patients compared to healthy controls
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Heritable ER stress impairs mitochondrial metabolism and maintenance of hematopoietic stem cells after low-dose irradiation.
PMID 41675062 · PMC12886522 · iScience · 2026 · 8 claims · 8 setups
Proliferating 20 mGy-irradiated HSC exhibit oxidative stress and altered metabolism with increased mitochondrial ROS and mitochondrial Ca2+ overload compared to non-irradiated HSC
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Identification and validation of lymphangiogenesis-related genes for predicting acute myeloid leukemia prognosis: insights from bulk RNA sequencing and single-cell RNA sequencing analyses.
PMID 41772327 · PMC12979290 · Clinical and experimental medicine · 2026 · 7 claims · 8 setups
A 6-LYMRG risk model (ANGPT1, HGF, MAPK8, PCNA, TBL1XR1, TLR4) is the optimal prognostic signature for AML
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Has reproduction · 63
A methyl-sensitive element induces bidirectional transcription in TATA-less CpG island-associated promoters.
PMID 30332484 · PMC6192621 · PloS one · 2018 · 8 claims · 8 setups
The CGCG element (consensus TCTCGCGAGA) is a novel promoter motif enriched in TATA-less CpG island-associated promoters of ribosomal protein and housekeeping genes
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Blood-based epigenetic instability linked to human aging and disease.
PMID 41690920 · PMC13018287 · Nature communications · 2026 · 7 claims · 8 setups
31,744 unmethylated (and 6143 methylated) CpG loci in blood show highly consistent, stable methylation in young healthy individuals and are defined as Epigenetically Stable Loci (ESLs)
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Increased IL4I1 expression predicts poor survival and modulates the immune microenvironment in acute myeloid leukemia.
PMID 41680858 · PMC12910993 · Journal of translational medicine · 2026 · 8 claims · 8 setups
IL4I1 mRNA expression is significantly elevated in AML compared to normal controls
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Epigenetic profiling of hematopoietic stem cells from male mice identifies KDR and PU.1 as regulators of aging transcriptome and caloric restriction response.
PMID 41720793 · PMC13035812 · Nature communications · 2026 · 8 claims · 8 setups
Lifelong CR reduces white blood cell production and shifts hematopoiesis toward myeloid and thrombo-erythroid lineages while suppressing lymphoid output
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Has reproduction · 84
An NMF-Based Methodology for Selecting Biomarkers in the Landscape of Genes of Heterogeneous Cancer-Associated Fibroblast Populations.
PMID 32425511 · PMC7218276 · Bioinformatics and biology insights · 2020 · 8 claims · 6 setups
An integrated methodology combining nonnegative matrix factorization (NMF), the WebGestalt functional enrichment tool, and an ad hoc gene extraction procedure automatically identifies informative gene subsets from microarray data matrices that differ in number of genes (rows) and patients (columns)