Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 37
Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength.
PMID 34534438 · PMC8585507 · Immunity · 2021 · 8 claims · 6 setups
TCR signal strength drives dynamic and time-dependent transcriptional changes in CD4+ T cells in vivo
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Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade.
PMID 41593194 · PMC13004670 · Nature medicine · 2026 · 8 claims · 5 setups
PD-1 blockade induces tumor-specific IgG1+ plasma cell responses that complement cellular immunity and contribute to clinical benefit