Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 66
Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo.
PMID 35784648 · PMC9243631 · Cell reports methods · 2022 · 8 claims · 7 setups
A purification-free hyperTRIBE method (FMR1-ADARcd-V5) can identify stress granule RNAs in bulk and single Drosophila S2 cells and in Drosophila neurons
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Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade.
PMID 41593194 · PMC13004670 · Nature medicine · 2026 · 8 claims · 5 setups
PD-1 blockade induces tumor-specific IgG1+ plasma cell responses that complement cellular immunity and contribute to clinical benefit
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Has reproduction · 72
Single-cell transcriptomics identifies Keap1-Nrf2 regulated collective invasion in a Drosophila tumor model.
PMID 36321803 · PMC9708074 · eLife · 2022 · 7 claims · 5 setups
Follicle cell-specific Lgl knockdown (Lgl-KD) causes loss of apical-basal polarity and invasive multilayering of the follicular epithelium without long-distance metastasis
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HIV-1 sequence evolution in vivo after superinfection with three viral strains.
PMID 17716368 · PMC2020475 · Retrovirology · 2007 · 8 claims · 8 setups
gag and env-V3 nucleotide evolution follows a similar pattern in all three strains: low substitution rate in the first 2-3 years of infection, then an increase driven mainly by synonymous substitutions
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EpCAM supports exit from pluripotency of embryonic stem cells via Eomes.
PMID 41963283 · PMC13076738 · Cell death & disease · 2026 · 8 claims · 8 setups
EpCAM supports exit from pluripotency of mESCs and is required for cardiomyocyte formation in embryoid bodies
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Remodeling of XIST regulatory landscape during primate evolution.
PMID 41544163 · PMC12810636 · Science advances · 2026 · 8 claims · 8 setups
XIST regulation has diverged uniquely and rapidly between closely related primates: JPX is a major XIST regulator in human and marmoset ESCs but only a minor regulator in macaque ESCs
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Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders.
PMID 41653922 · PMC13034722 · Molecular cell · 2026 · 8 claims · 8 setups
Heterozygous de novo missense mutations in RING1 and RNF2 are found in individuals with neurodevelopmental/intellectual disability phenotypes