Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans.
PMID 16848906 · PMC1543620 · Molecular pain · 2006 · 8 claims · 5 setups
COMT SNP5 (rs740603, intron 1) shows significant association with maximum post-operative pain rating
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Genetics and irritable bowel syndrome: from genomics to intermediate phenotype and pharmacogenetics.
PMID 19655247 · PMC2903621 · Digestive diseases and sciences · 2009 · 8 claims · 8 setups
Candidate gene association studies with IBS symptom phenotype (e.g., SLC6A4, GNB3, IL-10) have generally produced inconsistent, unreplicated results.
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A clinical genetic method to identify mechanisms by which pain causes depression and anxiety.
PMID 16623937 · PMC1488826 · Molecular pain · 2006 · 8 claims · 4 setups
Pain-triggered depression/anxiety are mediated by distinct spino-parabrachial-hypothalamic-amygdalar neurochemical pathways compared to mood disorders independent of pain
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Integrated weighted gene co-expression network analysis with an application to chronic fatigue syndrome.
PMID 18986552 · PMC2625353 · BMC systems biology · 2008 · 8 claims · 6 setups
Integrated WGCNA (IWGCNA), which adds genetic marker-based causality testing to standard WGCNA, can identify a disease-related module and its causal drivers