Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Investigation of the human tear film proteome using multiple proteomic approaches.
PMID 18334958 · PMC2268847 · Molecular vision · 2008 · 8 claims · 6 setups
Tear collection method (capillary vs. Schirmer strip) significantly impacts which proteins are detected in the tear film proteome.
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iTRAQ proteomic identification of pVHL-dependent and -independent targets of Egln1 prolyl hydroxylase knockdown in renal carcinoma cells.
PMID 19159641 · PMC2716563 · Advances in enzyme regulation · 2009 · 7 claims · 4 setups
Egln1 knockdown induces P1465 hydroxylation and Ser5 phosphorylation of Rpb1 only in VHL(+) cells, not VHL(-) cells
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Biomarkers of lupus nephritis determined by serial urine proteomics.
PMID 18596723 · PMC2614389 · Kidney international · 2008 · 7 claims · 6 setups
SELDI-TOF-MS screening of the LMW urine proteome identifies protein ions that are differentially expressed across phases of the lupus nephritis flare cycle (baseline, pre-flare, flare, post-flare)
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Microproteomics: analysis of protein diversity in small samples.
PMID 18271009 · PMC2743962 · Mass spectrometry reviews · 2008 · 8 claims · 8 setups
Changes in gene/mRNA expression often do not correlate well with changes in protein expression, due to precursor cleavage, post-translational modification, localization, and variable protein lifetimes.