Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• PW1(+) cells give rise to cardiac adipocytes during development and myofibroblasts following injury.

  PMID 42035143 · PMC13255232 · Stem cell research & therapy · 2026 · 8 claims · 8 setups

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  PW1+ cardiac mesenchymal cells serve as a progenitor population that gives rise to cardiac adipocytes during postnatal heart development

  heart pw1 sorted non-cardiomyocyte quantitative genetic adipogenesis

• Cardiac conduction system malformations in heterotaxy result from dysregulated Pitx2 expression.

  PMID 41734036 · PMC13043103 · JCI insight · 2026 · 8 claims · 8 setups

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  Cryptic-/- embryos (right isomerism model) develop bilateral sinoatrial nodes and an ectopic anterior AV node and bundle, accompanied by reduced Pitx2 expression

  cryptic embryo pitx2 lefty1 situ immunostaining cardiac

• Rtf1-dependent transcriptional pausing regulates cardiogenesis.

  PMID 41537425 · PMC12807453 · eLife · 2026 · 8 claims · 7 setups

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  Rtf1 activity is essential for differentiation of the myocardial lineage from mesoderm

  zebrafish embryo embryonic mescs crispr situ shrna

• TGFβ-activated PDHB promotes mitochondrial pyruvate metabolism and contributes to human endoderm differentiation via ATP-dependent BRG1.

  PMID 41702907 · PMC13022444 · Nature communications · 2026 · 8 claims · 8 setups

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  DE differentiation requires a TGFβ-driven metabolic switch characterized by reduced lactate production and enhanced TCA cycle activity/oxidative phosphorylation, mediated by PDHB

  escs crispr flow qrt-pcr