Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 50
Spatial transcriptomics demonstrates the role of CD4 T cells in effector CD8 T cell differentiation during chronic viral infection.
PMID 36450262 · PMC9792173 · Cell reports · 2022 · 8 claims · 6 setups
IL-21-producing Tfh CD4 T cells repopulate after CD4 depletion but remain at reduced frequency compared with control mice
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Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine-Dependent Pro-Inflammatory Immune Microenvironment.
PMID 41580972 · PMC13042394 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · 8 claims · 8 setups
T cell-specific Socs1 loss intrinsically drives pro-inflammatory T cell differentiation independent of antigen stimulation, with the strongest effects in CD8+ T cells
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CD38 expression by neonatal human naive CD4+ T cells shapes their distinct metabolic and tolerogenic properties.
PMID 41746743 · PMC13078883 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups
CD38 is markedly more highly expressed on cord blood (CB) naive CD4+ T cells than adult blood (AB) naive CD4+ T cells, with an age-dependent gradient from fetal to pediatric life.
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α4 Integrin blockade impairs CD8+ T cell neuroimmune surveillance following SIV infection.
PMID 41734020 · PMC13078879 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups
α4 blockade preserves CD4+ Th1 cell access to brain parenchyma but impairs CD8 effector recruitment, disrupting antiviral control