Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: splenocytes ✕ Assay: cd4+ ✕ Clear

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine-Dependent Pro-Inflammatory Immune Microenvironment.

PMID 41580972 · PMC13042394 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · 8 claims · 8 setups

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T cell-specific Socs1 loss intrinsically drives pro-inflammatory T cell differentiation independent of antigen stimulation, with the strongest effects in CD8+ T cells

cd45+ splenic cd8+ sorted single-cell flow bulk
Spatial transcriptomics demonstrates the role of CD4 T cells in effector CD8 T cell differentiation during chronic viral infection.

PMID 36450262 · PMC9792173 · Cell reports · 2022 · 8 claims · 6 setups

Has reproduction · 50

IL-21-producing Tfh CD4 T cells repopulate after CD4 depletion but remain at reduced frequency compared with control mice

cd44+ splenocytes spleen tcr scrna-seq flow spatial
Emergence of recombinant forms of HIV: dynamics and scaling.

PMID 17967052 · PMC2041978 · PLoS computational biology · 2007 · 7 claims · 5 setups

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A detailed mathematical model incorporating multiple cell infections and recombination quantitatively captures experimental observations of recombinant HIV emergence dynamics in vitro

cd4+ scid-hu splenocytes computational single-round replication-competent proviral
Aryl Hydrocarbon Receptor Ligands Drive Pancreatic Cancer Initiation and Progression through Protumorigenic T-cell Polarization.

PMID 40905825 · PMC12793834 · Cancer discovery · 2026 · 8 claims · 8 setups

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AHR ligands (cigarette smoke extract and TCDD) promote PDAC tumor growth in a syngeneic orthotopic mouse model

pdac naïve il22 orthotopic naïve western
Matcha alleviates sneezing response in a murine model of allergic rhinitis.

PMID 41786771 · PMC13022397 · NPJ science of food · 2026 · 8 claims · 8 setups

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Matcha suppresses allergen-induced immediate nasal response (INR) and nasal hyperresponsiveness (NHR) in an OVA-immunized mouse model

balb fecal cd4+ expanded sneeze nasal serum
Modified H5 promoter improves stability of insert genes while maintaining immunogenicity during extended passage of genetically engineered MVA vaccines.

PMID 19969118 · PMC2821965 · Vaccine · 2010 · 7 claims · 8 setups

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rMVA expressing multiple antigens under the mH5 promoter exhibit remarkable genetic stability and maintain potent immunogenicity after serial passage

rmva-infected individually bhk-21 pbmc qpcr western southern

Experiments

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine-Dependent Pro-Inflammatory Immune Microenvironment.

Spatial transcriptomics demonstrates the role of CD4 T cells in effector CD8 T cell differentiation during chronic viral infection.

Emergence of recombinant forms of HIV: dynamics and scaling.

Aryl Hydrocarbon Receptor Ligands Drive Pancreatic Cancer Initiation and Progression through Protumorigenic T-cell Polarization.

Matcha alleviates sneezing response in a murine model of allergic rhinitis.

Modified H5 promoter improves stability of insert genes while maintaining immunogenicity during extended passage of genetically engineered MVA vaccines.