Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Single-Cell Multi-Tissue T Cell Clonal Dynamics Reveal Distinct Immune Coercion Landscapes in MSI and MSS Colorectal Cancer.
PMID 41898550 · PMC13027115 · International journal of molecular sciences · 2026 · 8 claims · 5 setups
Immunotherapy response in CRC is better explained by TCR clonal dynamics (expansion, migration, functional transitions) than by MSI status alone
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A tumor-intrinsic WNT-inhibitory NOTUM program drives immune resistance in microsatellite stable colorectal cancer.
PMID 42097145 · PMC13198260 · Cell reports. Medicine · 2026 · 8 claims · 7 setups
A distinct NOTUM/NKD1/APCDD1-high, WNT-inhibitory cancer cell population (WICC) emerges predominantly in advanced-stage MSS CRC
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Has reproduction · 45
Single-Cell Analysis Reveals Characterization of Infiltrating T Cells in Moderately Differentiated Colorectal Cancer.
PMID 33584715 · PMC7873865 · Frontiers in immunology · 2020 · 8 claims · 8 setups
Eight distinct T cell populations can be identified from CRC tumor tissue by unsupervised clustering of scRNA-seq data
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CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance.
PMID 41564866 · PMC12866162 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
CHD1 and MAP3K7 loss additively sensitizes cancer cells to IFN-γ-induced death