Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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A cell atlas of multiple liver organoids and the fetal liver based on scRNA-seq.
PMID 41736863 · PMC12927097 · iScience · 2026 · 8 claims · 8 setups
A unified liver organoid cell atlas of 217,025 high-quality cells was constructed by integrating scRNA-seq data from 15 organoid samples across 9 studies with human fetal liver data (5-19 weeks gestation)
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Has reproduction · 92
Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration.
PMID 34773081 · PMC8589952 · Communications biology · 2021 · 8 claims · 7 setups
Large-scale integration of 111 sc/snRNAseq datasets captures rare, transitional myogenic progenitor states (commitment and fusion) that are poorly represented in individual datasets.
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Has reproduction · 50
Heterogeneity of cancer-associated fibroblasts in head and neck squamous cell carcinoma.
PMID 37320872 · PMC10277597 · Translational oncology · 2023 · 8 claims · 9 setups
Seven distinct CAF subsets exist in HNSCC, identified via integration of scRNA-seq, bulk transcriptomic, and spatial transcriptomic data.
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Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes.
PMID 41643060 · PMC13073339 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · 8 claims · 7 setups
Testicular endothelial cells (TECs) function as a central signaling hub coordinating intercellular communication within the human testicular interstitium
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Has reproduction · 75
Single-cell dissection of chronic lung allograft dysfunction reveals convergent and distinct fibrotic mechanisms.
PMID 41122970 · PMC12581678 · JCI insight · 2025 · 8 claims · 8 setups
CLAD exhibits specific cellular subsets including Fibro.AT2 cells, exhausted CD8+ T cells, and superactivated macrophages
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Has reproduction · 98
Systems spatiotemporal dynamics of traumatic brain injury at single-cell resolution reveals humanin as a therapeutic target.
PMID 35951114 · PMC9372016 · Cellular and molecular life sciences : CMLS · 2022 · 8 claims · 8 setups
Coordinated gene expression patterns across cell types are disrupted and re-organized by mTBI with distinct regional, cellular, and temporal (24-h vs 7-day) specificity.
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Migratory Tumor Cells Cooperate with Cancer Associated Fibroblasts in Hormone Receptor-Positive and HER2-Negative Breast Cancer.
PMID 38892065 · PMC11172245 · International journal of molecular sciences · 2024 · 8 claims · 8 setups
HR+/HER2-BC tumor epithelial cells comprise four single-cell-defined functional (SC-f) subtypes: migratory, secretory, proliferating, and dysfunctional.
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Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma.
PMID 41364805 · PMC13012255 · Blood cancer discovery · 2026 · 7 claims · 8 setups
IFN-γ signaling after autologous stem cell transplant (ASCT) is associated with markers of impaired CD8+ T-cell memory phenotype
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Single-cell sequencing analysis and machine learning model reveal aberrant TIM-3 expression in microglia during Alzheimer's disease progression.
PMID 41580850 · PMC12911240 · Journal of translational medicine · 2026 · 7 claims · 8 setups
A TIM-3+ microglial subset drives AD pathogenesis through a dual mechanism: sustained neuroinflammation via TNF-α/NF-κB and IL-6/JAK/STAT3 signaling, and impaired amyloid-β clearance linked to PI3K-AKT and FcγR pathways
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Spatial single-cell analysis reveals tumor microenvironment signatures predictive of oral cavity cancer outcome.
PMID 41707652 · PMC12923947 · Cell reports. Medicine · 2026 · 8 claims · 6 setups
Proliferating (KI67+) PROX1+ lymphatic endothelial cells (LECs) at the tumor invasive margin are a strong independent adverse prognostic factor for recurrence-free and overall survival in early-stage OSCC
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A pan-cancer single cell landscape reveals heterogeneity and functional diversity of double-negative T cells.
PMID 41484771 · PMC12882460 · Molecular cancer · 2026 · 7 claims · 5 setups
Integration of pan-cancer scRNA-seq data yields a comprehensive single-cell atlas of 157,025 high-quality DNT cells across 23 cancer types.
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Multi-cohort and single-cell profiling of aging genes reveals prognostic and therapeutic targets in breast cancer.
PMID 41732271 · PMC12924738 · iScience · 2026 · 8 claims · 7 setups
The eight-gene MLAG signature outperforms 100 previously published prognostic models across 12 independent breast cancer cohorts
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Homeodomain protein Sxi1α independently controls cell-cell fusion and gene expression during sexual reproduction in Cryptococcus deneoformans.
PMID 41818280 · PMC13001979 · PLoS genetics · 2026 · 8 claims · 8 setups
Sxi1α has a previously unrecognized inhibitory role in same-sex (α-α) cell-cell fusion during unisexual reproduction
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Has reproduction · 64
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils.
PMID 38358352 · PMC10903300 · Cancer research communications · 2024 · 8 claims · 7 setups
Two main neutrophil subtypes exist in primary tumors: an activated subtype sharing transcriptomic signatures with healthy neutrophils, and a tumor-specific subtype.