Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Sequencing the regulatory genome.

  PMID 18598374 · PMC2481419 · Genome biology · 2008 · 8 claims · 8 setups

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  Nuclear-lamina-associated domains (LADs) define chromatin regions with distinct transcriptional characteristics (fewer, lower-expressed genes, low RNA Pol II occupancy, H3K27me3-enriched borders)

  interphase nine beta-globin drosophila nuclear digital chip

• Locus-specific and activity-independent gene repositioning during early tumorigenesis.

  PMID 18195100 · PMC2213600 · The Journal of cell biology · 2008 · 7 claims · 6 setups

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  The genome undergoes global spatial reorganization during both normal and tumorigenic mammary epithelial differentiation, as shown by reduced nucleolar number.

  mcf-10a.b2 immunofluorescence interphase quantitative

• SOX2 phosphorylation during mitosis limits genomic damage.

  PMID 41213799 · PMC12863253 · Genes & development · 2026 · 8 claims · 8 setups

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  SOX2 (but not SOX9) remains dynamically bound to mitotic chromatin throughout all mitotic stages in neural stem cells

  sox2-halo nscs flag-wt-sox2 live-cell immunocytochemistry frap

• Mechanisms of gene regulation by SRCAP and H2A.Z.

  PMID 41792122 · PMC13087030 · Nature communications · 2026 · 8 claims · 8 setups

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  Acute SRCAP degradation causes rapid, genome-wide replacement of H2A.Z by canonical H2A, with turnover fastest at active promoters/enhancers and slower at bivalent loci

  syat cut&run live h2a.z