Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 74
Enforced MYC expression directs a distinct transcriptional state during plasma cell differentiation.
PMID 40721291 · PMC12305944 · Life science alliance · 2025 · 8 claims · 7 setups
Acute MYC (T58I) and BCL2 overexpression drives an aberrant B-cell differentiation phenotype with altered surface marker expression while functional antibody secretion is retained
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Transcription network construction for large-scale microarray datasets using a high-performance computing approach.
PMID 18366618 · PMC2386070 · BMC genomics · 2008 · 8 claims · 7 setups
RMT removes the random noise component of the gene expression correlation matrix by testing its eigenvalue statistics against a null hypothesis derived from a truly random correlation matrix
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FLASH-MM: fast and scalable single-cell differential expression analysis using linear mixed-effects models.
PMID 41644528 · PMC12982622 · Nature communications · 2026 · 8 claims · 6 setups
FLASH-MM produces LMM parameter estimates identical to lmer (lme4) up to the sixth decimal place while being 50- to 140-fold faster as sample size increases from 20,000 to 120,000 cells
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Prior-guided factorization for reliable imputation of scRNA-seq data.
PMID 41860953 · PMC13004523 · PLoS computational biology · 2026 · 8 claims · 8 setups
scZN models scRNA-seq counts as a mixture of a two-state (Gamma-Poisson/negative binomial) transcriptional bursting process and dropout, formalized via a zero-inflated negative binomial (ZINB) and solved as constrained nonnegative matrix factorization into a cell-to-cell-type assignment matrix and a cell-type expression matrix