Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Single cell multiomics revealed fibrotic trajectories of endometrial cells and interaction with the pro-fibrotic macrophages in intrauterine adhesion.

  PMID 41947225 · PMC13188631 · Genome medicine · 2026 · 8 claims · 8 setups

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  Human IUA endometrium contains a novel ACTA2+KRT8+ myofibrotic-epithelial subpopulation and an ACTA2+CD31+ myofibrotic-endothelial subpopulation, in addition to myofibroblasts

  endometrial iua scrna-seq snatac-seq spatial

• Single-cell and spatial transcriptome analysis reveals the potential therapeutic targets for testicular sex cord-stromal cell tumor.

  PMID 42057139 · PMC13130799 · Biomarker research · 2026 · 8 claims · 8 setups

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  Tumor areas of TSCST show significantly low expression of immune cell genes, indicating an immune-cold tumor microenvironment

  fresh fetal paraffin-embedded paraffin single-nucleus scrna-seq spatial

• Single-cell dissection of chronic lung allograft dysfunction reveals convergent and distinct fibrotic mechanisms.

  PMID 41122970 · PMC12581678 · JCI insight · 2025 · 8 claims · 8 setups

  Has reproduction · 75

  CLAD exhibits specific cellular subsets including Fibro.AT2 cells, exhausted CD8+ T cells, and superactivated macrophages

  clad covid-19 million formalin-fixed single-cell single-nucleus integrated

• Single-cell transcriptome analysis reveals DNMT1(+) epithelial cells promote lymphatic metastasis via CXCL17-mediated TAM infiltration.

  PMID 41845371 · PMC13107741 · Journal of translational medicine · 2026 · 8 claims · 8 setups

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  DNMT1+ epithelial cells, characterized by high epithelial-mesenchymal transition potential, show a propensity for lymph node metastasis in bladder cancer

  bladder scrna-seq um-uc-3 genomic single-cell cell-cell western

• Single-cell dissection of regulated cell death dynamics in ovarian aging.

  PMID 41689119 · PMC13005338 · Journal of ovarian research · 2026 · 8 claims · 8 setups

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  The RCD landscape of ovarian aging had not previously been characterized at single-cell resolution

  ovary serum scrna-seq bulk single-nucleus

• TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network.

  PMID 42020373 · PMC13102947 · Nature communications · 2026 · 8 claims · 8 setups

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  TBL/R1 are crucial regulators of β-cell identity and determinants of diabetes development and progression

  pancreatic fed paraffin-embedded pancreas qpcr blood oral

• Lung scRNA-seq reveals chronic inflammation and emphysemous phenotype in mice with osteogenesis imperfecta.

  PMID 41822759 · PMC12978693 · Frontiers in genetics · 2026 · 8 claims · 3 setups

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  Aga2 mice show increased alveolar spacing (emphysematous phenotype) at postnatal day 28 (p28) but not at p5

  lung histology single-cell rnascope

• A hormetic transcriptional program coregulates invasion, proliferation and dormancy to define metastatic potential.

  PMID 41781391 · PMC13077004 · Nature communications · 2026 · 8 claims · 7 setups

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  Prrx1 is a master regulator of dissemination that, beyond promoting invasion, represses proliferation (via Ccnd1/2, Cdkn2a/b/c) and activates a dormancy program (Gas6, Mme, Ogn)

  infiltrating metabric facs-sorted pymt immunohistochemistry bioinformatic rt-qpcr