Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Unveiling critical signaling pathways in the murine salivary gland and the role of midkine.
PMID 41732276 · PMC12925232 · iScience · 2026 · 8 claims · 6 setups
CellChat analysis of scRNA-seq data from E12, E14, and E16 murine SMG reveals distinct and evolving ligand-receptor signaling networks across developmental stages
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Pan-Cancer Single-Cell RNA Sequencing Analysis Refines Multi-Origin Monocyte and Macrophage Lineages.
PMID 41231218 · PMC12865363 · Cancer immunology research · 2026 · 6 claims · 8 setups
TAMs arise from two distinct origins: C1QC+ TAMs likely derive from resident tissue macrophages, while SPP1+ TAMs and ISG15+ TAMs likely originate from circulating monocytes.
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BMP and NODAL paracrine signalling regulate the totipotent-like cell state in embryonic stem cells.
PMID 41660012 · PMC12876259 · Frontiers in cell and developmental biology · 2025 · 7 claims · 8 setups
BMP and NODAL (TGF-β) paracrine signalling are key routes of intercellular communication that respectively enhance or diminish the totipotent-like cell (TLC) state in mouse ESCs
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Epigenetic context defines the transcriptional activity of canonical and noncanonical NF-κB signaling in pancreatic cancer.
PMID 41844578 · PMC13039881 · Cell death discovery · 2026 · 8 claims · 8 setups
TNFα is the primary activator of canonical NF-κB signaling via RELA in PDAC
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Single-cell RNA-sequencing of dermal fibroblasts demonstrates culture-induced changes and variable persistence of keloid disease features.
PMID 42058918 · PMC13123497 · iScience · 2026 · 7 claims · 6 setups
Fibroblast culture leads to subtype assimilation, with in vivo heterogeneity persisting only minimally by passage 4
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Differential cell signaling testing for cell-cell communication inference from single-cell data by dominoSignal.
PMID 41746282 · PMC12998610 · Bioinformatics (Oxford, England) · 2026 · 8 claims · 5 setups
dominoSignal extends the Domino algorithm to enable statistical testing of differential cell-cell signaling between experimental conditions.
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Mitochondrial DNA methylation predicts immunotherapy response and prognosis in lung adenocarcinoma: evidence from scRNA-Seq and machine learning.
PMID 41663976 · PMC12997902 · BMC cancer · 2026 · 8 claims · 8 setups
Differentially expressed MTDM-related genes (DEMTDMRGs) are significantly enriched in cell cycle regulation, ferroptosis, and ABC transporter pathways