Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 10

System / cell line: populations ✕ Assay: cellchat ✕ Clear

Unveiling critical signaling pathways in the murine salivary gland and the role of midkine.

PMID 41732276 · PMC12925232 · iScience · 2026 · 8 claims · 6 setups

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CellChat analysis of scRNA-seq data from E12, E14, and E16 murine SMG reveals distinct and evolving ligand-receptor signaling networks across developmental stages

submandibular smg e13.5 single immunofluorescence organ
Cis-regulatory evolution shapes facial diversity in birds and mammals.

PMID 42090501 · PMC13148318 · Science advances · 2026 · 8 claims · 6 setups

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Mesenchymal populations show markedly greater transcriptomic/regulatory divergence between mouse and chicken than ectodermal populations, pointing to a central role of mesenchyme in shaping facial morphology

embryo chicken embryos single-cell situ cross-species
Reciprocal regulation of fibroblast-macrophage equilibrium governs skin integrity.

PMID 41760904 · PMC13043295 · Nature immunology · 2026 · 8 claims · 8 setups

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Dpt+ fibroblasts are required to maintain skin macrophage populations in vivo; their depletion reduces CD64+ and CD11c+ macrophages

facs-sorted skin dpt+ scrna-seq flow cellchat
Assessing personalized molecular portraits underlying endothelial-to-mesenchymal transition within pulmonary arterial hypertension.

PMID 39462326 · PMC11513636 · Molecular medicine (Cambridge, Mass.) · 2024 · 8 claims · 8 setups

Has reproduction · 81

scRNA-seq of PAH and control lung tissue identifies nine distinct cell populations with high heterogeneity in composition, function, distribution, and communication

lung pah scrna-seq-derived endothelial scrna-seq bulk cell-cell
Developmental dynamics of catshark cranial neural crest cells provide insights into gnathostome facial evolution.

PMID 41987760 · PMC13200729 · Development (Cambridge, England) · 2026 · 8 claims · 8 setups

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The molecular toolkit of CNCCs is largely conserved across jawed vertebrates (gnathostomes)

scyliorhinus catshark chicken immunofluorescence single-cell umap
TGF-β-mediated activation of fibroblasts in cervical cancer: implications for tumor microenvironment and prognosis.

PMID 40124621 · PMC11929507 · PeerJ · 2025 · 8 claims · 8 setups

Has reproduction · 79

TGF-β signaling pathway activity is significantly increased in fibroblasts from cervical cancer samples compared to normal samples and correlates with tumor proliferation and differentiation.

cervical tcga-cesc hela scrna-seq scrna-seq wgcna cox
Hereditary chronic pancreatitis induced plasticity cooperates with mutant Kras in early pancreatic carcinogenesis.

PMID 41419303 · PMC13151493 · Gut · 2026 · 8 claims · 8 setups

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KC-Cpa1 mice show markedly increased pancreatic remodelling, fibrosis and metaplastic/PanIN lesion formation compared with KC mice

pancreas cre acinar scrna-seq histology bulk single-cell
Vγ1 γδ T cells steer airway macrophages toward a profibrotic response in an autochthonous lung cancer mouse model.

PMID 41779856 · PMC12959402 · Science advances · 2026 · 7 claims · 6 setups

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Lung tumors drive expansion of both CD27+ and CD27- pulmonary γδ T cells, which acquire distinct spatial and phenotypic changes in the tumor microenvironment

spc-cre+ microdissected sorted merged flow confocal single-cell
Single-cell analysis highlights the role of CD4(+) IFN-I-related T cells in Behcet's uveitis during Interferonα-2a therapy.

PMID 42021381 · PMC13238117 · Biology direct · 2026 · 6 claims · 8 setups

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CD4+ IFN-I-related T cells are significantly decreased in active BD patients and restored after IFNα-2a therapy

pbmcs sorted skin scrna-seq scrna-seq bulk cell-cell
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils.

PMID 38358352 · PMC10903300 · Cancer research communications · 2024 · 8 claims · 7 setups

Has reproduction · 64

Two main neutrophil subtypes exist in primary tumors: an activated subtype sharing transcriptomic signatures with healthy neutrophils, and a tumor-specific subtype.

colorectal sorted integrated neutrophil scrna-seq bulk immunohistochemistry

Experiments

Unveiling critical signaling pathways in the murine salivary gland and the role of midkine.

Cis-regulatory evolution shapes facial diversity in birds and mammals.

Reciprocal regulation of fibroblast-macrophage equilibrium governs skin integrity.

Assessing personalized molecular portraits underlying endothelial-to-mesenchymal transition within pulmonary arterial hypertension.

Developmental dynamics of catshark cranial neural crest cells provide insights into gnathostome facial evolution.

TGF-β-mediated activation of fibroblasts in cervical cancer: implications for tumor microenvironment and prognosis.

Hereditary chronic pancreatitis induced plasticity cooperates with mutant Kras in early pancreatic carcinogenesis.

Vγ1 γδ T cells steer airway macrophages toward a profibrotic response in an autochthonous lung cancer mouse model.

Single-cell analysis highlights the role of CD4(+) IFN-I-related T cells in Behcet's uveitis during Interferonα-2a therapy.

Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils.