Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Chromatin reorganization drives overexpression of a Btaf1 variant underpinning hematopoietic aging.
PMID 41851123 · PMC13149550 · Nature communications · 2026 · 8 claims · 6 setups
A chromatin loop forms between part of the Btaf1 gene and the whole Ide gene in old HSCs, accompanied by overexpression of a shorter Btaf1 variant (nBtaf1)
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Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation.
PMID 41477881 · PMC12850507 · Science (New York, N.Y.) · 2026 · 8 claims · 8 setups
A haplotype at the 17q22 locus, tagged by the noncoding variant rs17834140-T, is a causal protective variant against CHIP and myeloid malignancies
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Epigenetic profiling of hematopoietic stem cells from male mice identifies KDR and PU.1 as regulators of aging transcriptome and caloric restriction response.
PMID 41720793 · PMC13035812 · Nature communications · 2026 · 8 claims · 8 setups
Lifelong CR reduces white blood cell production and shifts hematopoiesis toward myeloid and thrombo-erythroid lineages while suppressing lymphoid output
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Glutamine-mediated crosstalk between M2 macrophages and tumor cells via the SLC38A5/FOXM1/CNIH4 axis promotes oral squamous cell carcinoma progression.
PMID 41715179 · PMC13020291 · Journal of translational medicine · 2026 · 8 claims · 8 setups
Glutamine secretion from M2 macrophages to tumor cells via SLC38A5 is the core mCCC pathway upregulated in metastatic OSCC lesions compared to primary lesions.
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RNA-binding protein LARP6 coordinates hepatic stellate cell activation and liver fibrosis.
PMID 41746718 · PMC13078889 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups
LARP6 is upregulated in activated hepatic stellate cells (A1/A2 subclusters) in human MASH and MetALD livers