Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 76
Topologically inferring pathway activity toward precise cancer classification via integrating genomic and metabolomic data: prostate cancer as a case.
PMID 26286638 · PMC4541321 · Scientific reports · 2015 · 6 claims · 6 setups
DRW-GM evaluates gene topological importance by directed random walk on a global gene–metabolite pathway graph integrating gene expression and metabolomic profiles to infer pathway activities
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Novel integrative genomics strategies to identify genes for complex traits.
PMID 16886998 · PMC2367618 · Animal genetics · 2006 · 8 claims · 7 setups
Forward genetics is restricted to genes harboring mutations, systematically missing network genes that causally influence disease without themselves being mutated.
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A variant of the SLC10A2 gene encoding the apical sodium-dependent bile acid transporter is a risk factor for gallstone disease.
PMID 19823678 · PMC2757911 · PloS one · 2009 · 6 claims · 4 setups
SLC10A2 is a novel susceptibility gene for cholelithiasis in humans