Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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The integrated world of functional genomics.
PMID 12537543 · PMC151279 · Genome biology · 2003 · 8 claims · 8 setups
Integrating chromatin immunoprecipitation (promoter-binding) data with expression data reveals the yeast cell-cycle transcriptional regulatory network, including network motifs such as autoregulation, multi-component loops, and feedforward loops.
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Has reproduction · 80
Progressive transformation of the HIV-1 reservoir cell profile over two decades of antiviral therapy.
PMID 36596305 · PMC9839361 · Cell host & microbe · 2023 · 8 claims · 7 setups
After long-term ART, intact HIV-1 proviruses are predominantly integrated in heterochromatin locations, most prominently centromeric satellite/micro-satellite DNA.
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CoMoDis: composite motif discovery in mammalian genomes.
PMID 17130158 · PMC1702496 · Nucleic acids research · 2007 · 7 claims · 4 setups
CoMoDis is a new bioinformatics tool that streamlines computational identification of novel regulatory modules starting from a single seed motif
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In silico meets in vivo.
PMID 18304380 · PMC2374716 · Genome biology · 2008 · 8 claims · 8 setups
About 10% of positions in multiple sequence alignments of the human genome with other vertebrate genomes are likely incorrect.
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TFBScluster web server for the identification of mammalian composite regulatory elements.
PMID 16845063 · PMC1538905 · Nucleic acids research · 2006 · 7 claims · 5 setups
TFBScluster is a web server that identifies genome-wide clusters of TFBSs conserved in multiple mammalian species using human or mouse as the reference genome.
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A naturally occurring human RPA subunit homolog does not support DNA replication or cell-cycle progression.
PMID 19942684 · PMC2817474 · Nucleic acids research · 2010 · 8 claims · 7 setups
Exogenous RPA4 expression does not support chromosomal DNA replication and causes cell-cycle arrest in G2/M
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CTCFBSDB: a CTCF-binding site database for characterization of vertebrate genomic insulators.
PMID 17981843 · PMC2238977 · Nucleic acids research · 2008 · 7 claims · 8 setups
CTCF is the only identified trans-acting factor in vertebrates that confers enhancer-blocking insulator activity
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The UCSC Genome Browser Database: update 2006.
PMID 16381938 · PMC1347506 · Nucleic acids research · 2006 · 8 claims · 8 setups
The UCSC Genome Browser Database (GBD) provides integrated sequence and annotation data, with web tools (Genome Browser, Table Browser, Proteome Browser, Gene Sorter, BLAT, In Silico PCR) for visualizing and querying genomes of about a dozen vertebrate species and several model organisms.