Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• CIRCE: a scalable Python package to predict cis-regulatory DNA interactions from single-cell chromatin accessibility data.

  PMID 41734268 · PMC12987762 · Bioinformatics (Oxford, England) · 2026 · 8 claims · 5 setups

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  CIRCE re-implements the Cicero co-accessibility algorithm in Python, producing near-identical results while running much faster and using far less memory

  bmmc pbmc foetal cis-regulatory enhancer-promoter scalability

• CircleBase V2: an eccDNA annotation platform across cancers and species.

  PMID 41273082 · PMC12807720 · Nucleic acids research · 2026 · 8 claims · 7 setups

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  CircleBase V2 provides a 12-fold increase in human eccDNA data, comprising over 3.8 million entries from >300 cell types/tissues

  raw eccdna tissues cancer circle-seq motif gene

• Chromosome-scale genome assembly and annotation of the two-spotted cricket Gryllus bimaculatus (Orthoptera: Gryllidae).

  PMID 41678355 · PMC13042277 · G3 (Bethesda, Md.) · 2026 · 8 claims · 8 setups

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  A chromosome-scale genome assembly of the white-eyed mutant G. bimaculatus strain was generated using ONT + PacBio HiFi long reads integrated with Hi-C data

  bimaculatus nanopore pacbio hi-c

• Chromosome-level genome assembly of the blackchin tilapia (Sarotherodon melanotheron).

  PMID 41942530 · PMC13234295 · Scientific data · 2026 · 7 claims · 7 setups

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  A chromosome-level genome assembly of blackchin tilapia was generated with total length 1,027.41 Mb and scaffold N50 of 38.87 Mb, with 93.42% of sequence anchored to 22 chromosomes.

  muscle ten illumina assembled illumina ont hi-c

• Nucleosome regulatory dynamics in response to TGFβ.

  PMID 24771338 · PMC4066760 · Nucleic acids research · 2014 · 8 claims · 7 setups

  Has reproduction · 59

  SuMMIt, a Bayesian strand-based mixture model requiring support from both ends of sequenced fragments, enables precise nucleosome mid-position calling, fuzziness scoring and between-condition change detection.

  hepatocellular hepg2 130-bp mnase strand-specific taqman

• A statistical framework for consolidating "sibling" probe sets for Affymetrix GeneChip data.

  PMID 18435860 · PMC2397416 · BMC genomics · 2008 · 7 claims · 4 setups

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  A two-way ANOVA model with a treatment x probe-set interaction term can automatically determine whether sibling probe sets for a gene behave similarly (non-significant interaction, consolidate) or differently (significant interaction, treat as independent)

  retina thyroid spermatogonial differentially two-way paired anova-based

• Telomere-to-telomere gapless genome assembly of Siniperca scherzeri.

  PMID 41927586 · PMC13216646 · Scientific data · 2026 · 8 claims · 8 setups

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  Integrated PacBio HiFi, ONT ultra-long reads, and Hi-C scaffolding to assemble a near-complete T2T genome of S. scherzeri

  genomic nuclear pooled assembled pacbio oxford illumina