Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes.

  PMID 41526351 · PMC12796357 · Nature communications · 2026 · 8 claims · 8 setups

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  Cardiomyocyte (CM)-specific Hi-C data detect substantially more and stronger promoter-interacting domains (PIDs) for CM marker genes than bulk cardiac tissue Hi-C data

  non-failing cardiac nf-lv-cm biological hi-c fluorescence-activated chip-seq

• The genome sequence of the Osiris Blue, Cupido osiris (Meigen, 1830) (Lepidoptera: Lycaenidae).

  PMID 41798706 · PMC12963831 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level genome assembly was produced for Cupido osiris (Osiris Blue butterfly)

  cupido pacbio hi-c k-mer

• The genome sequence of the European Pepper moth, Duponchelia fovealis (Zeller, 1847) (Lepidoptera: Crambidae).

  PMID 41929846 · PMC13040225 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level, haplotype-resolved genome assembly was generated for Duponchelia fovealis

  organism pacbio assembled pacbio hi-c k-mer

• The chromosomal genome sequence of the sponge, Rhopaloeides odorabile Thompson, Murphy, Bergquist & Evans, 1987 (Dictyoceratida: Spongiidae) and its associated microbial metagenome sequences.

  PMID 42232316 · PMC13224822 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level genome assembly was produced for the sponge Rhopaloeides odorabile using the Tree of Life pipeline

  rhopaloeides odorabile-associated odorabile recovered pacbio hi-c sequencing

• From linear genome sequence to three-dimensional organization of the cell nucleus.

  PMID 12620101 · PMC153456 · Genome biology · 2003 · 8 claims · 8 setups

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  Chromosome conformation capture (3C) can quantify in vivo physical interaction frequencies between genomic loci by crosslinking, digestion, and intramolecular ligation followed by PCR

  saccharomyces mitotic nucleoplasm hela chromosome translocation stretched

• The Nuclear and Mitochondrial Genomes of the Lined Rockskipper, Istiblennius lineatus (Teleostei: Blenniidae).

  PMID 42117780 · PMC13195801 · Genome biology and evolution · 2026 · 7 claims · 8 setups

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  A chromosome-scale nuclear genome assembly of I. lineatus (643.23 Mb, 24 pseudochromosomes) was generated using PacBio HiFi reads and Arima Hi-C scaffolding.

  istiblennius lineatus pacbio hi-c rna-seq

• Extrusion fountains are hallmarks of chromosome organization emerging upon zygotic genome activation.

  PMID 41690937 · PMC13018191 · Nature communications · 2026 · 8 claims · 8 setups

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  Fountains are a distinct class of Hi-C chromatin feature, different from TADs/stripes/compartments, that emerge as the earliest hallmark of chromosome organization shortly after ZGA in zebrafish

  danio zebrafish medaka xenopus hi-c chip-seq atac-seq

• The genome sequence of the Carline Skipper, Pyrgus carlinae (Rambur, 1839) (Lepidoptera: Hesperiidae).

  PMID 41841042 · PMC12989058 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level genome assembly was generated for a female Pyrgus carlinae specimen (ilPyrCarl1) as part of Project Psyche

  pyrgus pacbio hi-c k-mer

• Involvement of HTLV-I Tax and CREB in aneuploidy: a bioinformatics approach.

  PMID 16822311 · PMC1553470 · Retrovirology · 2006 · 8 claims · 6 setups

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  CTLL cells stably expressing wild-type Tax (CTLL/WT) show higher aneuploidy than a CREB-transactivation-deficient Tax clone (CTLL/703)

  ctll gene promoter metaphase microarray bioinformatics

• The Chromosome-Scale Genome Assembly of the Redlip Blenny, Ophioblennius macclurei (Blenniidae).

  PMID 41378738 · PMC12758960 · Genome biology and evolution · 2026 · 8 claims · 12 setups

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  A chromosome-scale genome assembly of O. macclurei was generated (529.6 Mb, scaffold N50 23.7 Mb, GC 43.49%) using ONT long reads, Illumina short reads, and Hi-C scaffolding.

  blood muscle tissues assembled oxford illumina hi-c

• Chromosome-level genome of the long-tailed marine-living ornate spiny lobster, Panulirus ornatus.

  PMID 38909031 · PMC11193758 · Scientific data · 2024 · 7 claims · 8 setups

  Has reproduction · 80

  A chromosome-level genome of P. ornatus was assembled spanning 2.65 Gb with contig N50 of 51.05 Mb, with 99.11% of sequence anchored to 73 chromosomes

  muscle eight genomic genome wgs hi-c rna-seq

• Chromosome-level genome assembly of agar-producing red seaweed Gracilaria vermiculophylla.

  PMID 41629338 · PMC12966425 · Scientific data · 2026 · 8 claims · 8 setups

  Has reproduction · 91

  Assembled the first chromosome-level genome of G. vermiculophylla: 77.5 Mb, 22 pseudochromosomes, contig N50 2.61 Mb, scaffold N50 3.16 Mb

  vermiculophylla assembled predicted genome short-read nanopore hi-c

• Improvements to GALA and dbERGE II: databases featuring genomic sequence alignment, annotation and experimental results.

  PMID 15608239 · PMC539999 · Nucleic acids research · 2005 · 8 claims · 8 setups

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  GALA is now a set of interlinked relational databases covering five vertebrate species: human, chimpanzee, mouse, rat and chicken.

  chromosome genomic comparative phylohmmcons conserved

• Chromosome-scale genome assembly for yellow wood sorrel, Oxalis stricta.

  PMID 41482730 · PMC12958822 · G3 (Bethesda, Md.) · 2026 · 8 claims · 8 setups

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  O. stricta genome assembly is chromosome-scale, 436 Mb, spanning 12 chromosomes across 2 subgenomes

  stricta long-read short-read hi-c

• Chromosome-level genome assembly of the deep-sea solemyid bivalve Acharax haimaensis.

  PMID 41760692 · PMC13066446 · Scientific data · 2026 · 7 claims · 9 setups

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  A. haimaensis genome was assembled to chromosome level (4.27 Gb, scaffold N50 195.52 Mb, anchored to 22 chromosomes) using PacBio HiFi, Illumina, and Hi-C sequencing

  acharax haimaensis illumina pacbio hi-c

• The chromosome-scale genome assembly and annotation of Rosa bracteata (Macartney Rose).

  PMID 41794947 · PMC13096426 · Scientific data · 2026 · 8 claims · 8 setups

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  A chromosome-scale genome assembly of R. bracteata totaling 540.63 Mb with contig N50 of 35.97 Mb was generated, with 501.06 Mb anchored onto seven pseudochromosomes.

  genomic root pacbio young pacbio hi-c rna-seq

• From 2D to 4D: a containerized workflow and browser to explore dynamic chromatin architecture.

  PMID 41507775 · PMC12870729 · BMC bioinformatics · 2026 · 8 claims · 3 setups

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  The 4DGBWorkflow and 4D Genome Browser (4DGB) are a containerized, cross-platform (macOS/Linux/Windows) toolkit that transforms Hi-C data into 3D chromosome reconstructions and provides comparative visualization

  a549 mus computationally hi-c molecular

• The genome sequence of the fin whale, Balaenoptera physalus (Linnaeus, 1758) (Artiodactyla: Balaenopteridae).

  PMID 41657664 · PMC12877476 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level genome assembly was produced for Balaenoptera physalus (fin whale) from a male specimen collected in Orkney, Scotland, as part of the Darwin Tree of Life project

  balaenoptera pacbio hi-c k-mer

• The genome sequence of the Gold Spangle, Autographa bractea (Denis & Schiffermüller), 1775 (Lepidoptera: Noctuidae).

  PMID 41710118 · PMC12910202 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level, haplotype-resolved genome assembly was produced for Autographa bractea (Gold Spangle)

  autographa pacbio hi-c k-mer

• The genome sequence of the Short-tailed Blue, Cupido argiades (Pallas, 1771) (Lepidoptera: Lycaenidae).

  PMID 41815329 · PMC12972722 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level genome assembly was produced for a female Cupido argiades specimen, comprising two haplotypes of 445.87 Mb and 384.46 Mb.

  organism pacbio assembled pacbio hi-c rna-seq