Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Integrative CSF profiling identifies disease-specific immune responses in leptomeningeal disease.

  PMID 41794040 · PMC13006398 · Cell reports. Medicine · 2026 · 8 claims · 8 setups

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  CSF exhibits distinct, disease-specific immune landscapes across CNSL, BrMs, and GB-associated LMD

  csf peripheral brain cell-free single-cell deep spatial

• Distinct phenotypes and repertoires of bronchoalveolar and airway mucosal T cells in health and allergic asthma.

  PMID 41519381 · PMC12983186 · Mucosal immunology · 2026 · 8 claims · 6 setups

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  BAL and endobronchial brush sampling capture phenotypically and clonally distinct T cell populations

  sorted paired bal subjects single-cell fluorescence-activated methacholine

• Unique phenotypic and T cell receptor characteristics of CD8(+) T cells accumulated in the brains of Alzheimer's disease mice.

  PMID 41794902 · PMC13087195 · Scientific reports · 2026 · 8 claims · 5 setups

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  Brain CD8+ T cells segregate into two major, mutually exclusive Trm populations: a CXCR6-related immunosuppressive cluster (cd8_c0) present in both aged non-Tg and 5xFAD_WT mice, and an AD-associated stem-like cluster (cd8_c1) present only in 5xFAD mice.

  brain-derived brain cd8+ clonally scrna-seq paired cellchat

• Multimodal framework for the joint analysis of single-cell RNA and T cell receptor sequencing data predicts T cell response to cancer immunotherapy.

  PMID 41820396 · PMC13121706 · Nature communications · 2026 · 8 claims · 7 setups

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  TRIM, a conditional multi-modal variational autoencoder integrating paired scRNAseq and scTCRseq data, predicts T cell clonality and transcriptional states at unmeasured tissue sites/timepoints.

  hnscc colorectal pan-cancer tcr paired umap convolutional

• Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

  PMID 19039135 · PMC2746051 · Science (New York, N.Y.) · 2008 · 8 claims · 7 setups

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  Diagnosis and relapse ALL samples show different patterns of CNAs, with relapse-acquired abnormalities preferentially affecting cell cycle regulation and B-cell development genes

  matched bone leukemia diagnosis snp flow quantitative

• Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory.

  PMID 41735532 · PMC12956582 · Nature immunology · 2026 · 8 claims · 8 setups

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  CD8+ T cells upregulate glycolysis to fuel anabolic needs for proliferation but predominantly use oxidative phosphorylation (OXPHOS) for energy production during the acute phase (days 7-28) after YFV vaccination

  peripheral cd8+ ns4b+ antigen-specific flow scrna-seq cite-seq