Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 40
5-HT reuptake blockade induces pyroptosis in BRAF(V600E)-mutated melanomas via remodeling histone serotonylation.
PMID 41494533 · PMC12866116 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
High-throughput screening of 90 FDA-approved antidepressants identifies PH as an alternative therapeutic for BRAF V600E-mutated melanoma
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Integrative single-cell analysis uncovers distinct tumour microenvironment ecotypes and immune evasion across skin cancers.
PMID 41636115 · PMC12869349 · Clinical and translational medicine · 2026 · 7 claims · 8 setups
A malignant NARS2+NDUFC2+ melanoma cell subpopulation with reduced MHC-I expression is enriched in advanced-stage tumours and associated with worse survival and immunotherapy response.
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CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance.
PMID 41564866 · PMC12866162 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
CHD1 and MAP3K7 loss additively sensitizes cancer cells to IFN-γ-induced death
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The transcription factor EHF promotes the maturation and immunosuppression of conventional dendritic cells.
PMID 41730908 · PMC13039115 · Nature communications · 2026 · 8 claims · 8 setups
EHF orchestrates an immunosuppressive maturation program in cDC1s and cDC2s downstream of TLR7/8/9 sensing of self-nucleic acids