Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 4

System / cell line: skin ✕ Assay: co-culture ✕ Clear

Lipid droplet-mediated macrophage reprogramming drives fibroblast activation in keloid-associated inflammation.

PMID 41840659 · PMC13063924 · Cell communication and signaling : CCS · 2026 · 8 claims · 8 setups

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Keloid-associated macrophages (KAM) and skin-associated macrophages (SAM) represent transcriptionally distinct populations, with KAM showing enhanced lipid metabolism and M2/pro-fibrotic signatures

skin keloid pbmc-derived macrophages single-cell immunofluorescence macrophage-sebocyte
Integrative single-cell analysis uncovers distinct tumour microenvironment ecotypes and immune evasion across skin cancers.

PMID 41636115 · PMC12869349 · Clinical and translational medicine · 2026 · 7 claims · 8 setups

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A malignant NARS2+NDUFC2+ melanoma cell subpopulation with reduced MHC-I expression is enriched in advanced-stage tumours and associated with worse survival and immunotherapy response.

skin prognosis melanoma macrophage single-cell bulk immunofluorescence
A macrophage-induced subpopulation of mesenchymal cells expressing Fcer1g contributes to wound-induced fibrosis.

PMID 41680182 · PMC13009336 · Nature communications · 2026 · 8 claims · 7 setups

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Early-phase macrophage depletion (MaFIA + AP20187) reduces fibrosis/scar area and mesenchymal cell numbers without delaying reepithelialization or angiogenesis.

mafia nih pdgfra-rtta flow excisional immunofluorescence
Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion.

PMID 17922906 · PMC2242664 · Breast cancer research : BCR · 2007 · 8 claims · 8 setups

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Tumor-derived fibroblasts promote higher levels of breast cancer cell invasion than normal fibroblasts

breast conditioned mda-mb-468 genomic invasion immunofluorescence pcr-rflp

Experiments

Lipid droplet-mediated macrophage reprogramming drives fibroblast activation in keloid-associated inflammation.

Integrative single-cell analysis uncovers distinct tumour microenvironment ecotypes and immune evasion across skin cancers.

A macrophage-induced subpopulation of mesenchymal cells expressing Fcer1g contributes to wound-induced fibrosis.

Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion.