Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Biotin tagging coupled with amino acid-coded mass tagging for efficient and precise screening of interaction proteome in mammalian cells.
PMID 19834888 · PMC4302342 · Proteomics · 2009 · 7 claims · 7 setups
BioCAT (biotin tagging + AACT) enables highly sensitive and accurate single-step screening of mammalian protein-protein interactions without establishing a stable cell line
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A map of human protein interactions derived from co-expression of human mRNAs and their orthologs.
PMID 18414481 · PMC2387231 · Molecular systems biology · 2008 · 8 claims · 6 setups
Comparing human mRNA co-expression with co-expression of orthologous gene pairs in five other organisms identifies proteins that physically associate
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LIMCH1-enriched extracellular vesicles promote vascular permeability in early-onset preeclampsia.
PMID 41604492 · PMC12851021 · Science advances · 2026 · 8 claims · 8 setups
LIMCH1 is identified as an Eo-PE-associated EV protein via serum sEV proteomics combined with GEO placental transcriptome datasets
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Has reproduction · 66
STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer.
PMID 32323921 · PMC7178451 · Molecular systems biology · 2020 · 8 claims · 6 setups
Low STAT3 expression in primary PCa is associated with increased OXPHOS and ribosomal biosynthesis at the transcriptomic level
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Neuroscience in the era of functional genomics and systems biology.
PMID 19829370 · PMC3645852 · Nature · 2009 · 8 claims · 7 setups
Omics/discovery-based approaches do not eschew hypotheses but elevate hypothesis testing to high-throughput hypothesis generation and prioritization.
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Cancer-wide in silico analyses using differentially expressed genes demonstrate the functions and clinical relevance of JAG, DLL, and NOTCH.
PMID 39074091 · PMC11285958 · PloS one · 2024 · 7 claims · 8 setups
JAG, DLL, and NOTCH family gene/protein expression varies diversely across 15 cancer types relative to normal tissue, sometimes discordant between mRNA and protein levels.