Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 67
Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.
PMID 34795257 · PMC8602323 · Nature communications · 2021 · 8 claims · 12 setups
PYK2 was identified as a putative IRF5 kinase via a kinase inhibitor library screen in macrophages
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Has reproduction
CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation.
PMID 31365872 · PMC6684324 · Cell reports · 2019 · 8 claims · 8 setups
Genome-wide CRISPR/Cas9 screens in CD40L-stimulated Daudi B cells identify known CD40/NF-κB pathway components plus many novel positive and negative CD40 regulators.
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Has reproduction
Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin.
PMID 16122393 · PMC1215486 · BMC neuroscience · 2005 · 8 claims · 8 setups
Plexin B3 strongly and plexin B2 moderately stimulate neurite outgrowth of primary murine cerebellar neurons
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Full-text index only
Report of the 9th HLPP Workshop October 2007, Seoul, Korea.
PMID 18683817 · PMC4601560 · Proteomics · 2008 · 8 claims · 8 setups
An integrated separating-identifying platform identified 6788 proteins (≥2 peptides, 95% confidence) in Chinese human liver samples, including 3721 new to liver and 977 hypothetical proteins