Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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SUPERFAMILY--sophisticated comparative genomics, data mining, visualization and phylogeny.
PMID 19036790 · PMC2686452 · Nucleic acids research · 2009 · 7 claims · 6 setups
SUPERFAMILY provides structural, functional and evolutionary annotation for proteins from all completely sequenced genomes using SCOP-based hidden Markov models
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MILANO--custom annotation of microarray results using automatic literature searches.
PMID 15661078 · PMC547913 · BMC bioinformatics · 2005 · 7 claims · 4 setups
MILANO annotates microarray gene lists by counting literature co-occurrences of each gene with user-defined secondary terms
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Identification and analysis of co-occurrence networks with NetCutter.
PMID 18781200 · PMC2526157 · PloS one · 2008 · 8 claims · 4 setups
Random sampling from a complete permutation set of the bipartite graph permits co-occurrence analysis with optimal stringency, and the edge-swapping (ES) model closely approximates this and is the preferred null-model among six tested.
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Unusual linkage patterns of ligands and their cognate receptors indicate a novel reason for non-random gene order in the human genome.
PMID 16277660 · PMC1309615 · BMC evolutionary biology · 2005 · 8 claims · 5 setups
Ligands are not more closely linked (shorter physical distance) to their cognate receptors than expected by chance
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BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments.
PMID 16845052 · PMC1538844 · Nucleic acids research · 2006 · 8 claims · 8 setups
Babelomics is presented as an updated, complete suite of web tools for functional analysis of genome-scale experiments with new and improved modules
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Has reproduction · 63
RummaGEO: Automatic mining of human and mouse gene sets from GEO.
PMID 39569206 · PMC11573963 · Patterns (New York, N.Y.) · 2024 · 8 claims · 7 setups
RummaGEO is a gene expression signature search engine built from automatically mined human and mouse RNA-seq perturbation studies in GEO
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A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus.
PMID 18631455 · PMC2727981 · Immunity · 2008 · 7 claims · 8 setups
Transcriptional modules constructed from coordinately expressed genes across 8 diseases form stable, biologically coherent functional units
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Seeded Bayesian Networks: constructing genetic networks from microarray data.
PMID 18601736 · PMC2474592 · BMC systems biology · 2008 · 8 claims · 4 setups
Seeding Bayesian Network analysis with prior networks derived from literature and/or PPI data improves recovery of known gene-gene interactions compared to BN analysis without a seed
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BRENDA, AMENDA and FRENDA: the enzyme information system in 2007.
PMID 17202167 · PMC1899097 · Nucleic acids research · 2007 · 7 claims · 6 setups
BRENDA is the largest publicly available enzyme information system worldwide, manually curated from primary literature and covering all identified enzymes regardless of source.
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The association of Alu repeats with the generation of potential AU-rich elements (ARE) at 3' untranslated regions.
PMID 15610565 · PMC544599 · BMC genomics · 2004 · 6 claims · 4 setups
Alu repeats are a source of AREs at 3' UTRs of human mRNA, via poly-A regions of Alu generating complementary poly-T/poly-U regions that acquire regular adenine insertions to form ARE motifs.
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FatiGO +: a functional profiling tool for genomic data. Integration of functional annotation, regulatory motifs and interaction data with microarray experiments.
PMID 17478504 · PMC1933151 · Nucleic acids research · 2007 · 8 claims · 8 setups
FatiGO+ is a web-based tool for functional profiling of genome-scale experiments that integrates functional annotation, regulatory motifs and interaction data
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Has reproduction · 48
Rbfox2 controls autoregulation in RNA-binding protein networks.
PMID 24637117 · PMC3967051 · Genes & development · 2014 · 8 claims · 8 setups
Rbfox2 cross-regulates AS-NMD events within RNA-binding protein genes to alter their expression, tuning autoregulatory splicing networks and placing Rbfox2 at a critical node of a multilayer regulatory network.