Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Identification of novel markers for liver fibrosis in HIV/hepatitis C virus coinfected individuals using genomics-based approach.
PMID 18614866 · PMC2654216 · AIDS (London, England) · 2008 · 8 claims · 6 setups
An 8-marker model combining six serum markers, age, and ART experience predicts liver fibrosis stage with an AUROC of 0.904.
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Use of proteomics for validation of the isolation process of clotting factor IX from human plasma.
PMID 19819359 · PMC2818390 · Journal of proteomics · 2010 · 8 claims · 8 setups
Proteomic techniques (LC-MS/MS, iTRAQ, immunochemical/biochemical methods) can monitor and validate each production step of pd F IX isolation
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Fibrinogen Yecheon: congenital dysfibrinogenemia with gamma methionine-310 to threonine substitution.
PMID 19949684 · PMC2775876 · Journal of Korean medical science · 2009 · 7 claims · 6 setups
A novel de novo heterozygous FGG mutation (c.1007T>C) causing γ Met310Thr substitution was identified in a Korean patient, named 'fibrinogen Yecheon'
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Human blood plasma preparation for two-dimensional gel electrophoresis.
PMID 17174613 · PMC7105212 · Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2007 · 8 claims · 6 setups
Plasma protein concentrations reflect the physiological/health state of an individual and can serve as disease biomarkers
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Late onset thrombosis in a case of severe protein S deficiency due to compound heterozygosity for PROS1 mutations.
PMID 18433462 · PMC2632602 · Journal of thrombosis and haemostasis : JTH · 2008 · 6 claims · 6 setups
A novel 14 bp deletion in intervening sequence L (putative branch point of intron L), which likely impairs PROS1 pre-mRNA splicing, was found in all family members with low free protein S.
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Proteomic characterization of plasma-derived clotting factor VIII-von Willebrand factor concentrates.
PMID 19768705 · PMC3030255 · Electrophoresis · 2009 · 8 claims · 8 setups
Commercial plasma-derived FVIII/VWF concentrates contain significant amounts of non-FVIII/VWF plasma proteins as impurities
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Clinical and molecular characterization of a re-established line of sheep exhibiting hemophilia A.
PMID 19943872 · PMC2826196 · Journal of thrombosis and haemostasis : JTH · 2010 · 7 claims · 7 setups
A line of hemophilia A (HA) sheep, extinct since the 1980s, was successfully re-established using cryopreserved semen and assisted reproductive technologies (MOET, IVF, ICSI)
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Integrating genomic based information into clinical warfarin (Coumadin) management: an illustrative case report.
PMID 18763667 · PMC3696193 · Connecticut medicine · 2008 · 8 claims · 6 setups
Combined CYP2C9 and VKORC1 genotype can explain up to 45% of warfarin dose variability
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Deletion of the V2 vasopressin receptor gene in two Chinese patients with nephrogenic diabetes insipidus.
PMID 17101063 · PMC1657029 · BMC genetics · 2006 · 7 claims · 6 setups
The two NDI patients carry a 5,995-bp genomic deletion combined with a 3-bp (GAG) insertion at Xq28 that removes the entire AVPR2 gene and the last exon (exon 22) of the C1 (ARHGAP4) gene.