Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Profiling critical cancer gene mutations in clinical tumor samples.
PMID 19924296 · PMC2774511 · PloS one · 2009 · 7 claims · 4 setups
OncoMap, a panel of ~400 mass-spectrometric genotyping assays targeting 33 cancer genes, enables robust mutation profiling of clinical fresh-frozen and FFPE tumor DNA.
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Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer.
PMID 16969349 · PMC2360724 · British journal of cancer · 2006 · 8 claims · 8 setups
K-Ras codon 12 mutations are significantly associated with metastatic (M+) CRC
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Targeted KRAS mutation assessment on patient tumor histologic material in real time diagnostics.
PMID 19888477 · PMC2768905 · PloS one · 2009 · 8 claims · 5 setups
Q-PCR methods yield informative KRAS mutation results even on very fragmented FFPE-DNA where dideoxy-sequencing fails (p<0.0001)
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Association between cyclo-oxygenase-2 overexpression and missense p53 mutations in gastric cancer.
PMID 11161397 · PMC2363738 · British journal of cancer · 2001 · 8 claims · 4 setups
p53 missense mutation is associated with COX-2 overexpression in gastric cancer
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TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival.
PMID 16229746 · PMC1276789 · BMC cancer · 2005 · 8 claims · 4 setups
Survival for BRCA1-familial ovarian cancer cases with TP53 mutations was not significantly different from familial cases without TP53 mutations (p=0.25, RR=1.64)