Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Chemical genomics: what will it take and who gets to play?
PMID 11423004 · PMC138939 · Genome biology · 2001 · 8 claims · 8 setups
Scaling chemical genetics to a genome-wide 'chemical genomics' requires large, well-funded, multidisciplinary centers that integrate compound libraries, protein resources, automation, and profiling technology, and freely distribute data and reagents.
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A methodological framework for the reconstruction of contiguous regions of ancestral genomes and its application to mammalian genomes.
PMID 19043541 · PMC2580819 · PLoS computational biology · 2008 · 8 claims · 5 setups
A general model-free methodological framework is proposed for reconstructing Contiguous Ancestral Regions (CARs) from conserved syntenies, generalizing prior computational and cytogenetic approaches
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Overview of microarray analysis of gene expression and its applications to cervical cancer investigation.
PMID 18182341 · PMC7129792 · Taiwanese journal of obstetrics & gynecology · 2007 · 6 claims · 5 setups
Oligonucleotide microarray and cDNA microarray are the two main microarray platforms used to study gene expression genome-wide.
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Local combinational variables: an approach used in DNA-binding helix-turn-helix motif prediction with sequence information.
PMID 19651875 · PMC2761287 · Nucleic acids research · 2009 · 8 claims · 7 setups
The LCV approach predicts HTH motifs with 93.29% accuracy, 93.93% sensitivity and 92.66% specificity using only primary sequence information
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Systems biology in human health and disease.
PMID 17893698 · PMC2013921 · Molecular systems biology · 2007 · 8 claims · 5 setups
High-throughput quantitative proteomics of signaling networks (e.g., HER2 overexpression) can be correlated with biological responses like proliferation and migration to better understand pathways deregulated in cancer.