Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Combinatorial Mismatch Scan (CMS) for loci associated with dementia in the Amish.
PMID 16515697 · PMC1448207 · BMC medical genetics · 2006 · 8 claims · 7 setups
CMS compares IBS allele/genotype sharing between distantly related (beyond grandparental) affected and unaffected individuals from founder populations to detect disease loci while reducing confounding from population stratification and genetic heterogeneity.
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Local combinational variables: an approach used in DNA-binding helix-turn-helix motif prediction with sequence information.
PMID 19651875 · PMC2761287 · Nucleic acids research · 2009 · 8 claims · 7 setups
The LCV approach predicts HTH motifs with 93.29% accuracy, 93.93% sensitivity and 92.66% specificity using only primary sequence information
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Identifying drug effects via pathway alterations using an integer linear programming optimization formulation on phosphoproteomic data.
PMID 19997482 · PMC2776985 · PLoS computational biology · 2009 · 7 claims · 4 setups
An ILP formulation of the Boolean pathway optimization problem fits phosphoproteomic data faster and more efficiently than the previously used genetic algorithm (GA) approach.
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Non-cross-linking gold nanoparticle aggregation as a detection method for single-base substitutions.
PMID 15640441 · PMC546178 · Nucleic acids research · 2005 · 8 claims · 7 setups
NCL aggregation of DNA-modified gold nanoparticles shows extraordinary selectivity against terminal mismatches at the free ends of surface-bound duplexes